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https://www.sciencedirect.com/science/article/pii/S1461534798000765
In practice, buccal drug delivery is considered when peroral drug delivery fails, such as in the case of peptides. Because of the low tissue permeability for compounds such as peptides, buccal administration is then often ranked as less effective when compared to nasal delivery, and better than transdermal delivery.Author: Janet A.J Hoogstraate, Philip W Wertz
https://www.sciencedirect.com/science/article/abs/pii/S1461534798000765
The buccal mucosa is one of the administration sites that might provide an alternative for peroral administration. This review will provide an insight into this route of drug delivery and the formulations that are, or can be, used, and it will also describe the challenges or possibilities of …Author: Janet A.J Hoogstraate, Philip W Wertz
https://pdfs.semanticscholar.org/b0a8/905cbaeb0f35d1770ebf43e550130f8bcdf4.pdf
sired effects of the drug. Buccal mucosa as a site for drug delivery There are two permeation pathways for passive drug transport across the oral mucosa: paracellular and transcellular routes. Permeants may traverse these two routes simultaneously, but one route usually is …
https://drug-dev.com/buccal-delivery-dissolvable-film-format-evolves-to-buccal-drug-delivery-applications/
As in transdermal drug delivery applications, the incorporation of chemical penetration enhancers can facilitate the transport of difficult APIs across the buccal mucosa and thereby allow for the delivery of compounds with a higher molecular weight. Some common penetration enhancers used to …
https://sites.ualberta.ca/~csps/JPPS1(1)/A.Shojaei/buccalreview.htm
Within the oral mucosal cavity, delivery of drugs is classified into three categories: (i) sublingual delivery, which is systemic delivery of drugs through the mucosal membranes lining the floor of the mouth, (ii) buccal delivery, which is drug administration through the mucosal membranes lining the cheeks (buccal mucosa), and (iii) local delivery, which is drug delivery into the oral cavity.
https://www.researchgate.net/publication/286714972_Systemic_drug_delivery_via_the_buccal_mucosal_route
Drug delivery through the buccal mucosa is an innovative method for local and systemic management since the buccal mucosa is permeable with high blood supply and permits long-time retention of the ...
https://www.europeanmedical.info/drug-delivery/absorption-of-drugs-across-the-oral-mucosa.html
Jan 24, 2020 · Within the oral cavity, delivery of drugs can be classified into four categories: (i) sublingual delivery in which the dosage form is placed on the floor of the mouth, under the tongue, (ii) buccal delivery, in which the formulation is positioned against the mucous membranes lining the cheeks, (iii) local oropharyngeal delivery to treat mouth and throat and (iv) periodontal delivery, to …
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