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http://news.mit.edu/2015/implantable-drug-delivery-microchip-device-0629
Jun 29, 2015 · An implantable, microchip-based device may soon replace the injections and pills now needed to treat chronic diseases: Earlier this month, MIT spinout Microchips Biotech partnered with a pharmaceutical giant to commercialize its wirelessly controlled, implantable, microchip-based devices that store and release drugs inside the body over many years.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299442/
The drug delivery microchip can release drug in a sustained manner after a lag phase, where the onset times and periods of delivery increase with the channel length. A problematic initial burst release was not observed with the microchips prepared in this work due to the presence of a channel as a resistive diffusion barrier.Author: Seung Ho Lee, Min Park, Chun Gwon Park, Ji Eun Lee, Mark R. Prausnitz, Young Bin Choy
https://www.webmd.com/osteoporosis/news/20120216/drug-delivery-microchip
Feb 16, 2012 · An experimental, implanted drug-delivery microchip that releases medication on command from an external wireless control could one day …Author: Salynn Boyles
https://newsatjama.jama.com/2012/02/16/drug-delivery-goes-wireless-via-microchip/
Drug Delivery Goes Wireless via Microchip By Rebecca Voelker on February 16, 2012 An implantable microchip (right) that’s no bigger than a computer memory stick is the first wireless programmable drug delivery device proven successful in a clinical study.
http://www.authorstream.com/Presentation/sanafatima319247-2982871-drug-20delivery-20system-20by-20microchip-20technology/
Dec 04, 2016 · conclusion Microchip for drug delivery system is a potential system that allows the storage and dependable, controlled release of multiple drugs . This device is less complex and much more dependable than the devices that attempt to control drug release rate .
https://www.medscape.com/viewarticle/758825
Nov 04, 2019 · Osteoporosis Drug Delivery via Wireless Microchip. February 17, 2012 — Researchers have conducted the first-in-human clinical trial of an implantable, wirelessly controlled microchip that can be programmed to deliver medication to patients with osteoporosis.
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/1.1.pdf
Microchip drug delivery system is the most wonderful system of delivering the drug for a great span of time without the intervention of the patient to whom it is fixed. It consists of varied number of sockets containing drug (generally ranging from 50-300) which release the drug …
https://www.hindawi.com/journals/bmri/2016/1743472/
Design and Components. Implanted microchips enable on-demand drug release [5, 12, 13]. Solid silicon microchips consist of hundreds of reservoirs filled with up to 1 mL drugs in an aseptic solid, liquid, or gel filing [14, 15].Author: Adam E. M. Eltorai, Henry Fox, Emily McGurrin, Stephanie Guang
https://stm.sciencemag.org/content/4/122/122ra21.full
Feb 22, 2012 · This paper describes the first human trial of an implantable drug delivery device based on microchip reservoir technology that is wirelessly programmable over the Medical Implant Communications Service (MICS) band to deliver an anti-osteoporosis drug at precise times (Fig. 1, A to C). The primary objective of this clinical trial was to assess the PK of hPTH(1–34) released from …Author: Robert Farra, Norman F. Sheppard, Laura McCabe, Robert M. Neer, James M. Anderson, John T. Santini, ...
https://darebioscience.com/microchips-biotech/
Microchips’ innovative drug delivery technology is designed to store and precisely deliver hundreds of therapeutic doses over months or years in a single implant. The implant is intended to be operated by the patient to deliver medication on demand or on a pre-determined schedule that can be activated or deactivated wirelessly, as required.
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