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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661099/
Mar 15, 2013 · Strategies that Use Drug Carriers for Drug Delivery to Brain Tumors. Recent advances in nanotechnology have created exciting opportunities to improve the efficiency of drug delivery to the CNS. 18, 19, 86 – 88 In principle, a drug that is poorly distributed to the brain can be loaded onto a nanocarrier system that interacts with the ...Author: Tali Siegal
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752842/
In another dimension of the delivery strategies, the invasive strategies, local delivery of chemotherapeutic agents to brain tumors by CED improves drug distribution compared to other strategies only driven by diffusion, however, this technique is also confounded by the notable side effects.Author: Valentino Laquintana, Adriana Trapani, Nunzio Denora, Fan Wang, James M Gallo, Giuseppe Trapani
http://www.eurekaselect.com/157831/article
The review summarizes novel drug delivery based treatment strategies for tumor targeting. Methods: Conventional surgical or chemotherapy based strategies are less efficient for treating brain cancer. Surgery is risky because extracting the tumors can permanently damage the brain and alter the patient's ability to function.Author: Viral Shah, Pratiksha Kochar
https://www.sciencedirect.com/science/article/pii/S2211383514000288
In this review, we briefly describe physiological and pathological conditions of brain tumors, including blood–brain/brain tumor barriers, tumor microenvironment and tumor stem cells; we review the corresponding targeting delivery strategies and introduce a systematic targeted drug delivery strategy to overcome current challenges.Author: Xiaoli Wei, Xishan Chen, Man Ying, Weiyue Lu
https://www.sciencedirect.com/science/article/pii/S2211383515001069
The recent advances, clinical benefits and business potentials of these technologies are discussed in detail. The potential benefits of insoluble drug delivery technologies are depicted in Fig. 1. Download : Download full-size image; Figure 1. Benefits of insoluble drug delivery strategies.Author: Sandeep Kalepu, Vijaykumar Nekkanti
https://www.researchgate.net/publication/338723648_Size-Tunable_Strategies_for_a_Tumor_Targeted_Drug_Delivery_System
In this review, we summarize series of stimuli-induced aggregation and shrinkage strategies for tumor targeted drug delivery, which can significantly increase the retention and penetration of ...
https://www.researchgate.net/publication/221977667_Recent_advances_in_drug_delivery_strategies_for_treatment_of_ovarian_cancer
Recent advances in drug delivery strategies for treatment of ovarian cancer Article · Literature Review in Expert Opinion on Drug Delivery 9(5):567-83 · March 2012 with 144 Reads
http://www.thno.org/v10p4557.htm
The stimuli-responsive nanocarriers for drug delivery to tumors towards precision imaging, effective therapy and theranostics. The nanocarriers could accumulate and penetrate tumors, and target cancer cells for achieving different applications and functions by responding to the external and internal stimuli. (Click on the image to enlarge.)
https://www.thno.org/v08p1481.htm
Drug delivery researchers need to consider aging influences when they design novel drug delivery systems for CNS diseases. Conclusion and future direction This review has covered recent strategies to deliver drugs to the brain in the past five years.
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