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https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance into the body and improves its efficacy and safety by controlling the rate, time, and place of release of drugs in the body.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The controlled drug delivery technology has progressed over the last six decades. It began in 1952 with the introduction of the first sustained release formulation. The 1st generation (1950-1980) of drug delivery was focused on developing oral and transdermal sustained release systems and establishing the controlled drug release mechanisms.Author: Kinam Park
https://link.springer.com/chapter/10.1007/978-981-10-0503-9_1
Jul 13, 2018 · Each drug has some pharmacological properties that can produce biological effects on the human body; these effects are engendered by the interactions between the drug and specific receptors at the drug’s site of action. This is a preview of subscription content, log in to check access.Author: Hamid Reza Rezaie, Mohammadhossein Esnaashary, Abolfazl Aref arjmand, Andreas Öchsner
https://www.sciencedirect.com/science/article/pii/B9780081019979000011
It is worth to mention that during the same period, the history of drug delivery was dramatically changed when the ALZA Corporation was founded in 1968 by Alejandro Zaffaroni . The ALZA Corporation was unique as its business model was not to create new drugs, but to better enable drug therapy by delivering the drugs at the right place and the right time [14] (i.e., targeted and controlled release).Author: Nedal Y. Abu-Thabit, Abdel Salam H. Makhlouf
https://www.researchgate.net/publication/326349744_The_History_of_Drug_Delivery_Systems
For more than 60years drug delivery systems have produced numerous controlled release formulations helping patients improve compliance and maximize the drug efficacy. Development of new controlled...
https://liposomes.weebly.com/history1.html
The History and Progress of Liposomes in Medicine 1965: Alec Bangham described the first closed bilayer phospholipid systems, first called "bangosomes," now called liposomes. 1971: Gregory Gregoriadis proposed the use of liposomes for drug delivery.
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in the near future.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403087/
Mar 18, 2015 · Clonidine, approved by the US Food and Drug Administration (FDA) in 1984 for up to 1 week transdermal delivery to manage mild-to-moderate hypertension (Sica and Grubbs, 2005), was first applied to facial skin in the form of a shaving lotion, a soap or a cream for its pilomotor effect (Zeile et al., 1965), in which the stimulation of the arrector pili muscle of the skin causes goose bumps so that hairs …Author: Michael N Pastore, Yogeshvar N Kalia, Michael Horstmann, Michael S Roberts, Michael S Roberts
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