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https://www.sciencedirect.com/science/article/pii/S0032386108000487
Hydrogels used in drug delivery are usually formed outside of the body and impregnated with drugs before placement of the hydrogel–drug complex in the body. A wide range of cross-linking strategies can be used, including UV photopolymerization and various chemical cross-linking techniques.Author: Todd R. Hoare, Daniel S. Kohane
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898614/
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs and cells.Author: Jianyu Li, David J. Mooney
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs …Author: Jianyu Li, David J. Mooney
https://www.sciencedaily.com/releases/2019/09/190918093103.htm
Sep 18, 2019 · Bio-engineering researchers have created a biocompatible, protein-based hydrogel that could serve as a drug delivery system durable enough to survive in …
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.9b01020
A hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and can achieve sustained delivery of a drug at tumor sites. In addition, hydrogels have excellent biocompatibility and biodegradability and lower toxicity than nanoparticle carriers. Smart hydrogels can respond to stimuli in the environment (e.g., heat, pH, light, and ultrasound), enabling in situ gelation and controlled drug …Author: Zhaoyi Sun, Chengjun Song, Chao Wang, Yiqiao Hu, Jinhui Wu
https://www.sciencedirect.com/science/article/pii/S0144861720302484
Gallic acid is used in the study as an active marker of Cortex Moutan and so, the PF127 hydrogel drug delivery system involving polysaccharide-based nano-conjugate could be effectively used for loading Cortex Moutan in the treatment of AD via textile-based transdermal therapy. Moreover, this study can help to develop a non-invasive treatment method for AD by applying TCM.Author: Sudipta Chatterjee, Patrick Chi-leung Hui, Elaine Wat, Chi-wai Kan, Ping-Chung Leung, Wenyi Wang
https://www.hindawi.com/journals/ijps/2019/3160732/
The hydrogels incorporating CaCO 3 exhibited higher drug entrapment efficiency and longer sustained drug release than NaHCO 3, indicating that CaCO 3 is a viable pore-forming agent for the development of an effective floating drug delivery system .Author: Ke Wang, Yuting Hao, Yingna Wang, Jinyuan Chen, Lianzhi Mao, Yudi Deng, Junlin Chen, Sijie Yuan, Tia...
http://www.orientjchem.org/vol29no3/hydrogels-smart-materials-for-drug-delivery/
The pharmaceutical industry has been developing hydrogel based drug delivery system in an advanced manner by tuning the structure, shape and surface modifications of the biopolymers. The present review highlights the role of hydrogels in drug delivery. It also highlights the use of important polymers and their applications in drug delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568318/
Feb 05, 2013 · There are several relevant extensions of the technology platform. For example, more than one drug could be tethered to a hydrogel by one or more individually tuned linkers to provide a delivery system that releases the drug combination at the same or different rates.Author: Gary W. Ashley, Jeff Henise, Ralph Reid, Daniel V. Santi
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