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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826320/
Oct 28, 2013 · These exciting evidences suggested that Lf-R might be a promising candidate for hepatocellular carcinoma targeting due to its high affinity for ASGP-R, and developing a hepatic carcinoma targeting drug delivery system employing the ASGP-R targeting ability of Lf-R is highly possible. Lacto Bionic Acid (LA) Ligand.Author: Nidhi Mishra, Narayan Prasad Yadav, Vineet Kumar Rai, Priyam Sinha, Kuldeep Singh Yadav, Sanyog Jain...
https://www.sciencedirect.com/topics/neuroscience/hepatic-portal-system
The main vessel of the hepatic portal system is the hepatic portal vein (Figures 3.31 and 3.32), a large vein that lies in the gastrohepatoduodenal ligament alongside the hepatic artery and anterior part of the bile duct.The hepatic portal vein is formed by the confluence of three main vessels, the gastric, pancreaticomesenteric, and lienomesenteric veins.
https://quizlet.com/44880866/vn-131-study-guide-ch-23-gi-flash-cards/
Start studying VN 131 STUDY GUIDE CH. 23 GI. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Search. ... c. hepatic portal circulation d. small intestine. d. small intestine. the word hepatic refers to the a. pancreas ... c. delivery of chyme to the duodenum d. all of the above.
https://www.sciencedirect.com/topics/medicine-and-dentistry/enterohepatic-circulation
J.B. Watkins III, C.D. Klaassen, in Comprehensive Toxicology, 2010. 10.06.1 Introduction. Enterohepatic circulation involves substances that are metabolized in the liver, excreted into the bile, and passed into the intestinal lumen; there they are reabsorbed across the intestinal mucosa and returned to the liver via portal circulation. The gastrointestinal tract is also an important barrier to ...
https://www.ncbi.nlm.nih.gov/books/NBK53073/
The Hepatic circulation is unique among vascular beds. The most obvious unique features include the dual vascular supply; the mechanism of intrinsic regulation of the hepatic artery (the hepatic arterial buffer response); the fact that portal blood flow, supplying two thirds of liver blood flow, is not controlled directly by the liver; the fact that 20% of the cardiac output rushes through the ...
https://quizlet.com/219461562/pharmacology-ch-4-adams-flash-cards/
The length of time required for the plasma concentration of a drug to decrease by half after administration. -The greater the half-life, the longer it takes to excrete-If a PT has extensive renal or hepatic disease, teh plasma half life of a drug will increase, and the drug …
https://www.researchgate.net/publication/330428745_Sublingual_route_for_systemic_drug_delivery
Bypass GI tract and hepatic portal syst em and ... drugs directly goes to systemic circulation via sublingual drug delivery and bypassing the gastrointestinal tract and hepatic first-pass ...
https://en.wikipedia.org/wiki/Hepatic_portal_system
Clinical significance. Portal hypertension is a condition in which the blood pressure of the portal venous system is too high. It is often the result of cirrhosis of the liver.. Drug metabolism. Many drugs that are absorbed through the GI tract are substantially metabolized by the liver before reaching general circulation. This is known as the first pass effect.
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