Dna Vaccine Delivery Systems

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DNA Vaccines—How Far From Clinical Use?

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274812/
    Nov 15, 2018 · More recently, the DNA vaccine delivery properties of orally applied bacteria, for example with regard to phagolysosomal escape have been improved by additional coating with NC . Compared with other sytemic routes of DNA vaccination, pulmonary application of aerolized DNA vaccines is a rather new approach .Author: Dominika Hobernik, Matthias Bros

Recent trends in vaccine delivery systems: A review

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465129/
    Vaccine drug delivery systems are gaining popularity these days due to the benefits they offer. Vaccine drug delivery systems are now being proven to be patient friendly as they avoid the need to administer booster doses and provide a long term therapy in small doses. Their use is further encouraged by administering them via needle-free ...

Nanotechnology in vaccine delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0169409X08000458
    Smaller particles on the order of 10–1000 nm in size pursued as vaccine delivery systems and immunopotentiators are the focus of this review. An additional characteristic shared by the nanosystems discussed herein is that they have all been at least preliminarily tested in the clinic (with the exception of polymeric nanoparticles). 2.Author: Laura J. Peek, C. Russell Middaugh, Cory Berkland

(PDF) Lipid-based mRNA vaccine delivery systems

    https://www.researchgate.net/publication/270002235_Lipid-based_mRNA_vaccine_delivery_systems
    Lipid-based mRNA vaccine delivery systems. Article ... lipids designed for DNA transfection, few of them have been. yet evaluated for mRNA transfection in vitro and in vivo [18, 19].

Improvement of different vaccine delivery systems for ...

    https://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-10-3
    Jan 07, 2011 · These polymers have been designated as feasible candidates for drug delivery systems, anti-cancer agents and vaccine immunotherapy. For example, DNA vaccine delivery to APCs has been facilitated by microencapsulation of plasmid DNA, which encodes HPV E6/E7 antigenic proteins. The capsule is formed from polymeric PGLA microparticles.Author: Azam Bolhassani, Shima Safaiyan, Sima Rafati

Cationic microparticles: A potent delivery system for DNA ...

    https://www.pnas.org/content/97/2/811
    Jan 18, 2000 · DNA coadministered with microparticles, but not adsorbed, does not induce a similar effect to adsorbed DNA. The theory that delivery of DNA to APCs is an important component of the mechanism of enhancement is further supported by the observation that large microparticles (>30 μm) failed to elicit a potent immune response, whereas smaller ...Author: Manmohan Singh, Maylene Briones, Gary Ott, Derek O'Hagan

Systemically administered gp100 encoding DNA vaccine for ...

    https://www.sciencedirect.com/science/article/pii/S0378517313004316
    The objective of this study was to develop the W/O/W multiple emulsions-based delivery system for human gp100 encoding plasmid DNA vaccine for melanoma immunotherapy. The human gp100 encoding cDNA fragment was inserted between multiple cloning sites of the OmicsLink™ Expression Clone to create gp100 plasmid DNA vaccine.Author: Mayurkumar Kalariya, Mansoor M. Amiji

(PDF) Recent trends in vaccine delivery systems: A review

    https://www.researchgate.net/publication/232257539_Recent_trends_in_vaccine_delivery_systems_A_review
    Recent trends in vaccine delivery systems: A review ... plant-derived viruses which are now being investigated and developed as vaccine delivery systems. This paper also describes various aspects ...

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