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http://www.nature.com/articles/nbt0100_33
Jan 01, 2000 · Most DNA delivery systems operate at one of three general levels: DNA condensation and complexation, endocytosis, and nuclear targeting/entry. Negatively charged DNA molecules are usually condensed...Author: Dan Luo, W. M. Saltzman
https://www.ncbi.nlm.nih.gov/pubmed/28661127
Aug 14, 2017 · The core concept behind multifunctional polymeric DNA delivery systems is to endow one single DNA carrier, via materials engineering and surface modification, with several active functions, e.g., good cargo DNA protection, excellent colloidal stability, high cellular uptake efficiency, efficient endo/lysosome escape, effective import into the nucleus, and DNA unpacking.Author: Bingyang Shi, Meng Zheng, Wei Tao, Roger Chung, Dayong Jin, Dariush Ghaffari, Omid C. Farokhzad
https://www.sciencedirect.com/science/article/pii/S0378517313010351
Hydrodynamic gene delivery is an easier approach used to insert DNA effectively into the internal organs, especially the liver (Zhang et al., 1999). It was first used in 1996 by Budker and his team who succeeded in inserting plasmid DNA into the skeletal muscle of rats by rapid injection into the femoral artery (Budker et al., 1998).Author: D. Ibraheem, A. Elaissari, H. Fessi
https://www.sciencedirect.com/science/article/pii/B9780081005576000043
In vivo delivery of DNA in Balb/c mice resulted in the highest gene expression in the spleen. In another variant, high molecular weight bPEI was cross-linked with dimethylsuberimidate (Fig. 4.5) and synthesized a series of bPEI NPs by varying the amounts of the cross-linker (Tripathi et al., 2013b).Author: Manohar Mahato, Ashwani Kumar Sharma, Pradeep Kumar
https://scialert.net/fulltext/?doi=biotech.2008.385.402
PTP based transformation is an injection/delivery of naked DNA into ovaries to produce transformed progeny (Touraev et al., 1997). In this approach the stigma is cut off and a drop of DNA solution is …
https://www.thermofisher.com/us/en/home/references/gibco-cell-culture-basics/transfection-basics/selecting-a-viral-dna-delivery-system.html
There are many options in selecting a viral delivery system matched to your specific needs. Life Technologies™ offers a variety of viral vector systems for delivering nucleic acids into mammalian and insect cells for protein expression and RNAi studies.
https://www.ncbi.nlm.nih.gov/pubmed/29151352
Dec 20, 2017 · Plasmid DNA molecules with unique loop structures have widespread bioapplications, in many cases relying heavily on delivery vehicles to introduce them into cells and achieve their functions.Author: Hao Song, Meihua Yu, Yao Lu, Zhengying Gu, Yannan Yang, Min Zhang, Jianye Fu, Chengzhong Yu
https://pubs.acs.org/doi/abs/10.1021/acs.nanolett.7b04812
The self-assembled DNA nanokite achieves efficient gene delivery and exhibits effective inhibition of tumor growth in vitro and in vivo without apparent systemic toxicity.Author: Jianbing Liu, Linlin Song, Linlin Song, Shaoli Liu, Shaoli Liu, Qiao Jiang, Qing Liu, Qing Liu, Na L...
A reputation that delivers. The Owners and Directors of DNA, Danielle & Tony Bunn, maintain the key to the success of the business to date has been as a result of the principles and values that they have always upheld and stayed true to over the last 15 years.
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