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https://pubs.acs.org/doi/abs/10.1021/acsami.6b00959
Severe side effects of cancer chemotherapy prompt developing better drug delivery systems. Injectable hydrogels are an effective site-target system. For most of injectable hydrogels, once delivered in vivo, some properties including drug release and degradation, which are critical to chemotherapeutic effects and safety, are challenging to monitor.Author: Jia Liu, Chao Qi, Kaixiong Tao, Jinxiang Zhang, Jian Zhang, Luming Xu, Xulin Jiang, Yunti Zhang, Lei...
https://www.sciencedirect.com/science/article/pii/S0141813019364189
Targeted drug delivery system (TDDS) is a drug controlled release system, also known as targeted preparations, which can selectively act on target organs, target tissues and target cells [, , ]. Another hotspot of dextran research is its application in drug carriers. …Author: Fang Chen, Gangliang Huang, Hualiang Huang
https://www.researchgate.net/publication/331682236_Preparation_and_drug_delivery_of_dextran-drug_complex
Mar 11, 2019 · Dextran will be a potential carrier for the delivery of antitumor drugs in the future, which provides the possibility of slow-release chemotherapy and targeted drug delivery.
https://www.sciencedirect.com/science/article/pii/S0141813019337377
Dextran with good biocompatibility and degradability shows great potentials for drug delivery and tissue engineering applications. Electro-responsive drug delivery system can provide on-demand and localized drug release. However, dextran-based conductive hydrogel with electrical stimuli responsiveness as drug delivery system has not been reported.Author: Jin Qu, Yongping Liang, Mengting Shi, Baolin Guo, Yanzheng Gao, Zhanhai Yin
https://web.wpi.edu/Pubs/E-project/Available/E-project-042506-120742/unrestricted/Drug_Delivery_Final_MQP_2006.pdf
An ideal drug delivery method releases the drug through zero order kinetics, resulting in a slower, more controlled drug release and a steady concentration of drug within the body. Controlled drug release helps to guard against toxicity problems because it prevents the initial spike of the drug substance that occurs with uncontrolled
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · Silver nanoparticles exhibited antimicrobial activity, but as for drug delivery, very few studies have been carried out, for example, Prusty and Swain synthesized an inter-linked and spongy polyacrylamide/dextran nano-hydrogels hybrid system with covalently attached silver nanoparticles for the release of ornidazole which turned out to have an ...Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141874/
Drug release profile of nanocomplexes showed a fast DOX release followed by a slow sustained release, leading to release of 32% of entrapped DOX within 15 days. DOX-DS nanocomplexes may serve as a drug delivery system with efficient drug encapsulation and also may be taken into consideration in designing DOX controlled-release systems.Author: Parisa Yousefpour, Fatemeh Atyabi, Ebrahim Vashegani Farahani, Ramin Sakhtianchi, Rassoul Dinarvand
https://academic.oup.com/jac/article/68/11/2576/834791
Jun 24, 2013 · Divya Prakash Gnanadhas, Midhun Ben Thomas, Monalisha Elango, Ashok M. Raichur, Dipshikha Chakravortty, Chitosan–dextran sulphate nanocapsule drug delivery system as an effective therapeutic against intraphagosomal pathogen Salmonella, Journal of Antimicrobial Chemotherapy, Volume 68, Issue 11, November 2013, Pages 2576–2586, https://doi ...Author: Divya Prakash Gnanadhas, Midhun Ben Thomas, Monalisha Elango, Ashok M Raichur, Ashok M Raichur, Dips...
https://www.researchgate.net/publication/221876197_Dextran_conjugates_in_drug_delivery
Introduction: Dextran is a family of natural polysaccharides that is widely under investigation for use as polymeric carriers in novel drug delivery systems.
https://iopscience.iop.org/article/10.1088/2043-6254/ab0282/pdf
MNPs as drug delivery system [14–16]. In this paper we present a new approach of using microwave for dextran car-boxymethylation and MNPs synthesis. CMD at different degree of substitution (subtitution of –OH groups in glucose units of dextran by carboxylmethyl –OCH 2COOH groups) were fabricated and characterized. The MNPs were coatedAuthor: Hai Doan Do, Thi Thu Huong Le, Hong Nam Pham, Phuong Thu Ha
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