Design Of A Self Regulated Drug Delivery Device

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Design of a Self-Regulated Drug Delivery Device SpringerLink

    https://link.springer.com/article/10.1023/A:1011494008729
    Jun 01, 2001 · In this paper, we describe the design of a self-regulated drug delivery device based on the integration of both mechanical and chemical methods. In this device, a constant release rate can be achieved by carefully designing the shape of the drug reservoir, while a pH-sensitive hydrogel switch is used to regulate the drug release.Author: Xia Cao, Siyi Lai, L. James Lee

Design of a novel hydrogel-based intelligent system for ...

    https://www.sciencedirect.com/science/article/pii/S0168365903005662
    The present work focused on the design of an assembled drug delivery system (DDS) to provide multifunctions, such as drug protection, self-regulated oscillatory release, and targeted uni-directional delivery by a bilayered self-folding gate and simple surface mucoadhesion.Author: Hongyan He, Xia Cao, L.James Lee

with Potential for Self-Regulated Drug Delivery

    https://www.mdpi.com/1420-3049/24/6/1089/pdf
    glucose-sensitive gels for self-regulated drug delivery. The PBA-based glucose-sensitive gels, including hydrogels, microgels, and nanogels, are expected to significantly promote the development of smart self-regulated drug delivery systems for diabetes therapy. Keywords: phenylboronic acid; gel; glucose sensitivity; drug delivery; diabetes therapy 1.Author: Chenyu Wang, Bozhong Lin, Haopeng Zhu, Fei Bi, Shanshan Xiao, Liyan Wang, Guangqing Gai, Li Zhao

Evolution of Drug Delivery Devices: Bridging the gap ...

    https://decisionresourcesgroup.com/blog/evolution-drug-delivery-devices-bridging-gap-medtech-pharma/
    Nov 17, 2016 · The development of a drug delivery device can help extend the patent protection on a drug. For example, GlaxoSmithKline’s patent on Advair —a drug used for the treatment of asthma attacks and chronic obstructive pulmonary disease—expired …

Chemically self-regulated drug delivery systems ...

    https://www.sciencedirect.com/science/article/pii/0168365988900375
    TRIGGERED DRUG DELIVERY DEVICES A triggered drug delivery system is a device which contains an active agent and which re- mains passive until it is triggered by a change in the environment surrounding the device.Author: J. Heller

SELF-REGULATED DRUG DELIVERY SYSTEM

    https://pharmawiki.in/wp-content/uploads/2014/01/Multiple-Emulsions.pptx
    Multiple emulsions finds wide range of applications in controlled or sustained drug delivery, targeted delivery, taste masking, bioavailability enhancement, enzyme immobilization, etc. it will be able to provide a novel carrier system for drugs, cosmetics and pharmaceutical agents.

Designing hydrogels for controlled drug delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898614/
    The clinical use of drug delivery systems is appreciable 7, with a global market of over $150 US billion in 2013. Hydrogels are a particularly appealing type of drug delivery system, and have been used in many branches of medicine, including cardiology, oncology, immunology, wound healing…Author: Jianyu Li, David J. Mooney

Stimuli Sensitive Polymers and Self Regulated Drug ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142101/
    Sep 28, 2014 · “Stimuli responsive” and “self regulating” drug delivery systems have captured the imagination of researchers, in large part because they suggest a means to mimic the physiological homeostatic feedback mechanisms that are essential for health.Author: Ronald A. Siegel

Feedback regulated drug delivery system

    https://www.slideshare.net/surbhimadan7/feedback-regulated-drug-delivery-system
    Nov 22, 2018 · Self-regulated DDS This type of FR-DDS depends on a reversible and competitive binding mechanism to activate and to regulate the release of drug . In this system the drug reservoir is a drug complex encapsulated in a impermeable polymeric membrane. The release of drug from the delivery system is activated by the membrane permeation of a biochemical agent from the tissue in …

Polymers in Controlled Drug Delivery MDDI Online

    https://www.mddionline.com/polymers-controlled-drug-delivery
    Drug delivery from a typical matrix drug delivery system. For the reservoir systems shown in Figures 3a and 3b, the drug delivery rate can remain fairly constant. In this design, a reservoir whether solid drug, dilute solution, or highly concentrated drug solution within a polymer matrix is surrounded by a film or membrane of a rate-controlling material.

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