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https://onlinelibrary.wiley.com/doi/abs/10.1002/adtp.201900206
Efficient delivery of nucleic acid typically requires delivery vehicles to facilitate the entry of nucleic acid into cells. Among nonviral delivery vehicles, cationic materials are favored because of their high loading capacity for nucleic acids and prominent cellular uptake …Author: Ziwen Jiang, Ziwen Jiang, S. Thayumanavan
https://www.researchgate.net/publication/231755397_Designer_Materials_for_Nucleic_Acid_Delivery
This issue of MRS Bulletin on “Designer Materials for Nucleic Acid Delivery” explores the diverse materials—polymers, lipids, nanoparticles, biocompatible scaffolds, and engineered peptides ...
https://www.sciencedirect.com/science/article/pii/S0734975013001961
Research review paper Design, preparation and application of nucleic acid delivery carriers 1. Introduction. Nucleic acids, which include DNA (deoxyribonucleic acid) and RNA... 2. Liposome. Motivated by the structures of virus, lipids are used in the delivery vectors... 3. Polymersome. Polymer ...Author: Jun Yang, Hongmei Liu, Xin Zhang
https://www.researchgate.net/publication/339241196_Noncationic_Material_Design_for_Nucleic_Acid_Delivery
Noncationic design provides a class of materials for nucleic acid delivery with reduced toxicity profiles. These materials are designed via either neutralizing the cationic moieties within the...
https://pubs.acs.org/doi/pdfplus/10.1021/acsami.8b18790
Minimalist Design of a Stimuli-Responsive Spherical Nucleic Acid for Conditional Delivery of Oligonucleotide Therapeutics Hassan H. Fakih , Johans J. Fakhoury , Danny Bousmail , …
https://www.howard.edu/medicine/radiology/mil/docs/2015_BiomaterRes_Yang.pdf
Engineered biomaterials for development of nucleic acid vaccines. Jun Yang1, Yan Li1,4, Shubin Jin2, Jing Xu2, Paul C Wang3, Xing-Jie Liang2* and Xin Zhang1*. Abstract Nucleic acid vaccines have attracted many attentions since they have presented some superiority over traditional vaccines.
https://pubs.acs.org/doi/10.1021/acsami.8b18790
Minimalist Design of a Stimuli-Responsive Spherical Nucleic Acid for Conditional Delivery of Oligonucleotide Therapeutics Hassan H. Fakih Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, CanadaAuthor: Hassan H. Fakih, Johans J. Fakhoury, Danny Bousmail, Hanadi F. Sleiman
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/nucleic-acid-delivery
Direct surface immobilization of nucleic acids has been accomplished by adsorption of vectors to biomaterial surfaces, covalent conjugation of vectors to surfaces, binding of biotinylated vectors to avidin-modified surfaces or recognition of vector epitopes by antibody-conjugated surfaces ( …
https://academic.oup.com/nsr/article/6/6/1105/5307097
Feb 05, 2019 · The ideal nanoparticle in a nucleic acid delivery system should protect the gene against degradation by nucleases and internalize the plasma membrane, while escaping from the endosomal compartment. Subsequently, the nanodelivery system might unpackage the gene at some point with no detrimental effects, and the nanoparticle should also be less immunogenic and low in cost [ 2 ].Author: Xiawei Wei, Yuquan Wei
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