Design Materials For Nucleic Acid Delivery

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Noncationic Material Design for Nucleic Acid Delivery ...

    https://onlinelibrary.wiley.com/doi/abs/10.1002/adtp.201900206
    Efficient delivery of nucleic acid typically requires delivery vehicles to facilitate the entry of nucleic acid into cells. Among nonviral delivery vehicles, cationic materials are favored because of their high loading capacity for nucleic acids and prominent cellular uptake …Author: Ziwen Jiang, Ziwen Jiang, S. Thayumanavan

Designer Materials for Nucleic Acid Delivery

    https://www.researchgate.net/publication/231755397_Designer_Materials_for_Nucleic_Acid_Delivery
    This issue of MRS Bulletin on “Designer Materials for Nucleic Acid Delivery” explores the diverse materials—polymers, lipids, nanoparticles, biocompatible scaffolds, and engineered peptides ...

Design, preparation and application of nucleic acid ...

    https://www.sciencedirect.com/science/article/pii/S0734975013001961
    Research review paper Design, preparation and application of nucleic acid delivery carriers 1. Introduction. Nucleic acids, which include DNA (deoxyribonucleic acid) and RNA... 2. Liposome. Motivated by the structures of virus, lipids are used in the delivery vectors... 3. Polymersome. Polymer ...Author: Jun Yang, Hongmei Liu, Xin Zhang

Noncationic Material Design for Nucleic Acid Delivery ...

    https://www.researchgate.net/publication/339241196_Noncationic_Material_Design_for_Nucleic_Acid_Delivery
    Noncationic design provides a class of materials for nucleic acid delivery with reduced toxicity profiles. These materials are designed via either neutralizing the cationic moieties within the...

Minimalist Design of a Stimuli-Responsive Spherical ...

    https://pubs.acs.org/doi/pdfplus/10.1021/acsami.8b18790
    Minimalist Design of a Stimuli-Responsive Spherical Nucleic Acid for Conditional Delivery of Oligonucleotide Therapeutics Hassan H. Fakih , Johans J. Fakhoury , Danny Bousmail , …

Engineered biomaterials for development of nucleic acid ...

    https://www.howard.edu/medicine/radiology/mil/docs/2015_BiomaterRes_Yang.pdf
    Engineered biomaterials for development of nucleic acid vaccines. Jun Yang1, Yan Li1,4, Shubin Jin2, Jing Xu2, Paul C Wang3, Xing-Jie Liang2* and Xin Zhang1*. Abstract Nucleic acid vaccines have attracted many attentions since they have presented some superiority over traditional vaccines.

Minimalist Design of a Stimuli-Responsive Spherical ...

    https://pubs.acs.org/doi/10.1021/acsami.8b18790
    Minimalist Design of a Stimuli-Responsive Spherical Nucleic Acid for Conditional Delivery of Oligonucleotide Therapeutics Hassan H. Fakih Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, CanadaAuthor: Hassan H. Fakih, Johans J. Fakhoury, Danny Bousmail, Hanadi F. Sleiman

Nucleic Acid Delivery - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/nucleic-acid-delivery
    Direct surface immobilization of nucleic acids has been accomplished by adsorption of vectors to biomaterial surfaces, covalent conjugation of vectors to surfaces, binding of biotinylated vectors to avidin-modified surfaces or recognition of vector epitopes by antibody-conjugated surfaces ( …

Opportunities and challenges in the nanoparticles for ...

    https://academic.oup.com/nsr/article/6/6/1105/5307097
    Feb 05, 2019 · The ideal nanoparticle in a nucleic acid delivery system should protect the gene against degradation by nucleases and internalize the plasma membrane, while escaping from the endosomal compartment. Subsequently, the nanodelivery system might unpackage the gene at some point with no detrimental effects, and the nanoparticle should also be less immunogenic and low in cost [ 2 ].Author: Xiawei Wei, Yuquan Wei

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