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https://www.sciencedirect.com/science/article/pii/S1744165X06000540
Out of all of the suspected causes of preterm labour and delivery, infection and/or inflammation is the only pathological process for which both a firm causal link with preterm birth has been established and a molecular pathophysiology defined. Inflammation has also been implicated in the mechanism of spontaneous parturition at term.Author: Roberto Romero, Roberto Romero, Jimmy Espinoza, Jimmy Espinoza, Luís F. Gonçalves, Luís F. Gonçalves...
https://www.ncbi.nlm.nih.gov/pubmed/16839830
Inflammation has been implicated in the mechanisms responsible for preterm and term parturition, as well as fetal injury. Out of all of the suspected causes of preterm labour and delivery, infection and/or inflammation is the only pathological process for which both a firm causal link with preterm birth has been established and a molecular pathophysiology defined.Author: Roberto Romero, Roberto Romero, Jimmy Espinoza, Jimmy Espinoza, Luís F. Gonçalves, Luís F. Gonçalves...
https://jlb.onlinelibrary.wiley.com/doi/pdf/10.1189/jlb.3MR0615-272RR
well established that infection and inflammation repre-sent a highly significant risk factor in preterm birth. However, despite the clinical and public health signifi-cance, infectious agents, molecular trigger(s), and immune pathways underlying the pathogenesis of pre-term birth remain underdefined and represent a major gap in knowledge.Author: Monica Cappelletti, Silvia Della Bella, Enrico Ferrazzi, Domenico Mavilio, Senad Divanovic
https://www.researchgate.net/publication/6945513_Inflammation_in_preterm_labour_and_delivery
Out of all of the suspected causes of preterm labour and delivery, infection and/or inflammation is the only pathological process for which both a firm causal link with preterm birth has been established and a molecular pathophysiology defined.
https://www.ncbi.nlm.nih.gov/pubmed/26538528
Preterm birth is the leading cause of neonatal morbidity and mortality. Although the underlying causes of pregnancy-associated complication are numerous, it is well established that infection and inflammation represent a highly significant risk factor in preterm birth.Author: Monica Cappelletti, Silvia Della Bella, Enrico Ferrazzi, Domenico Mavilio, Senad Divanovic
https://www.sciencedirect.com/science/article/pii/S0165037818301906
Infection is a frequent cause of inflammation in preterm labor and delivery (Romero et al., 1998, Romero et al., 2007a). During pregnancy, extra-uterine infections such as malaria, pyelonephritis, pneumonia or periodontal disease are associated with premature parturition.Author: Alice Gilman-Sachs, Svetlana Dambaeva, Maria D. Salazar Garcia, Youssef Hussein, Joanne Kwak-Kim, Ke...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249583/
Dec 01, 2014 · Based on the observations that (i) intrauterine inflammation is elevated in preterm compared to term labor; (ii) culture positive amniotic-fluid infection is associated with more severe fetal inflammatory responses; and (iii) polymicrobial infections are more common in labor at earlier gestations, one might be tempted to conclude that a polymicrobial infection would equate to a more severe inflammatory …Author: Matthew W. Kemp
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242863/
Acute intrauterine viral exposure may result in preterm labor and delivery. Pregnant women are at higher risk of spontaneous preterm birth if they have circulating hepatitis B virus antigens. 29. Experimental models also suggest the possible induction of labor by viral infection.Author: Varkha Agrawal, Emmet Hirsch, Emmet Hirsch
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