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https://link.springer.com/article/10.1007%2Fs10989-008-9156-x
Oct 15, 2008 · The major drawbacks with conventional cancer chemotherapy are the lack of satisfactory specificity towards tumor cells and poor antitumor activity. In order to improve these characteristics, chemotherapeutic drugs can be conjugated to targeting moieties e.g. to peptides with the ability to recognize cancer cells.Author: Maarja Mäe, Helena Myrberg, Samir El-Andaloussi, Ülo Langel
https://pubs.acs.org/doi/10.1021/bc0701139
Nov 15, 2007 · The cyclic peptide cCPGPEGAGC (PEGA) is a homing peptide that has previously been shown to accumulate in breast tumor tissue in mice. PEGA peptide does not cross the plasma membrane per se; however, when attached to the cell-penetrating peptide pVEC, the conjugate is taken up by different breast cancer cells in vitro.Author: Helena Myrberg, Lianglin Zhang, Maarja Mäe, Ülo Langel
https://www.ncbi.nlm.nih.gov/pubmed/18001077
Therefore, an ideal anticancer drug should discriminate between normal tissue and tumors. This would require a target receptor molecule mostly present in tumors. The cyclic peptide cCPGPEGAGC (PEGA) is a homing peptide that has previously been shown to accumulate in breast tumor tissue …Author: Helena Myrberg, Lianglin Zhang, Maarja Mäe, Ülo Langel
https://www.researchgate.net/publication/225731471_Design_of_a_Tumor_Homing_Cell-Penetrating_Peptide_for_Drug_Delivery
Recently a design of a tumor homing CPP was reported. In this chimeric peptide a tumor homing peptide CREKA [182] was combined with a cell-penetrating peptide pVEC to yield a peptide with tumor homing specificity that can efficiently carry cargo molecules inside the cells [199].
https://pubs.acs.org/doi/abs/10.1021/bc0701139
The cyclic peptide cCPGPEGAGC (PEGA) is a homing peptide that has previously been shown to accumulate in breast tumor tissue in mice. PEGA peptide does not cross the plasma membrane per se; however, when attached to the cell-penetrating peptide pVEC, the conjugate is taken up by different breast cancer cells in vitro.Author: Helena Myrberg, Lianglin Zhang, Maarja Mäe, Ülo Langel
http://www.diva-portal.org/smash/record.jsf?pid=diva2:200171
The cyclic peptide cCPGPEGAGC (PEGA) is a homing peptide that has previously been shown to accumulate in breast tumor tissue in mice. PEGA peptide does not cross the plasma membrane per se; however, when attached to the cell-penetrating peptide pVEC, the conjugate is taken up by different breast cancer cells in vitro.
https://onlinelibrary.wiley.com/doi/abs/10.1111/cbdd.13537
Design of a new pH‐activatable cell‐penetrating peptide for drug delivery into tumor cells. This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record.Author: Yun Zhang, Li Li, Linlin Chang, Hui Liu, Jingjing Song, Yue Liu, Hexin Bao, Beijun Liu, Rui Wang, Ji...
https://www.researchgate.net/publication/5846070_Design_of_a_Tumor-Homing_Cell-Penetrating_Peptide
Therefore, an ideal anticancer drug should discriminate between normal tissue and tumors. This would require a target receptor molecule mostly present in tumors. The cyclic peptide cCPGPEGAGC (PEGA) is a homing peptide that has previously been shown to accumulate in breast tumor tissue …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327652/
Apr 16, 2012 · In this context, tumor homing peptides have drawn much attention. These peptides are playing a vital role in delivering drugs in tumor tissues with high specificity. In order to provide service to scientific community, we have developed a database of tumor homing peptides called TumorHoPe.Author: Pallavi Kapoor, Harinder Singh, Ankur Gautam, Kumardeep Chaudhary, Rahul Kumar, Gajendra P. S. Ragha...
https://www.sciencedirect.com/science/article/pii/S016561471200020X
Peptides for cell-selective drug delivery. Author links open overlay panel Nina Svensen Jeffrey ... bioinformatic design of a peptide library utilizing solved crystal structures with virtual docking of the peptides and their conformers can ... et al.Design of a tumor homing cell-penetrating peptide for drug delivery. Int. J. Pept. Res. Ther ...Author: Nina Svensen, Jeffrey G.A. Walton, Mark Bradley
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