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https://www.sciencedirect.com/topics/chemistry/micellar-drug
The micellar structures generated using surfactant molecules have been used in delivering poorly soluble or hydrophobic drugs. These micellar structures can be loaded with hydrophobic drugs during their assembly and can be used to release the drugs on application of a …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399483/
Jul 05, 2012 · Various techniques are used for the enhancement of the solubility of poorly soluble drugs which include physical and chemical modifications of drug and other methods like particle size reduction, crystal engineering, salt formation, solid dispersion, use of surfactant, complexation, and so forth.Author: Ketan T. Savjani, Anuradha K. Gajjar, Jignasa K. Savjani
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629443/
Aug 24, 2015 · Several marketed drugs were reformulated to improve efficacy, safety and patient compliance. In order to gain marketing exclusivity and patent protection for such products, revitalization of poorly soluble drugs using insoluble drug delivery technologies have been successfully adopted by many pharmaceutical companies.Author: Sandeep Kalepu, Vijaykumar Nekkanti
https://www.sciencedirect.com/science/article/pii/S2211383513000919
The therapeutic efficacy of a poorly water soluble drug can be improved by increasing its gastrointestinal solubilization with concomitant modification of pharmacokinetic profiles. Lipid-based drug delivery systems play an important role in the delivery of hydrophobic drugs with low bioavailability by using various lipids as carriers.Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://www.researchgate.net/publication/262380356_Polymeric_Micelles_for_the_Delivery_of_Poorly_Soluble_Drugs
Polymeric micelles have found wide application as pharmaceutical nanocarriers for the delivery of poorly soluble drugs. The poorly water-soluble drugs can easily get trapped in the hydrophobic ...
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.2042-7158.2010.01107.x
New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs jphp_1107 1622..1636 Anette Müllertza,b, Anayo Ogbonnaa, Shan Rena and Thomas Radesc aDepartment of Pharmaceutics and Analytical Chemistry, bBioneer:FARMA, The Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark and cSchool of Pharmacy, University …Author: Anette Müllertz, Anayo Ogbonna, Shan Ren, Thomas Rades
https://onlinelibrary.wiley.com/doi/full/10.1111/j.2042-7158.2010.01107.x
To summarise this section, we conclude that the LFCS is a practical and, by and large, useful attempt to order the plethora of lipid and surfactant based systems for oral delivery of poorly soluble drugs. We have, however, also highlighted some conceptional shortcomings of this system.Author: Anette Müllertz, Anayo Ogbonna, Shan Ren, Thomas Rades
https://www.researchgate.net/publication/8694837_Polymeric_Micelles_for_Delivery_of_Poorly_Water-Soluble_Compounds
Polymeric Micelles for Delivery of Poorly Water-Soluble Compounds Article · Literature Review in Critical Reviews in Therapeutic Drug Carrier Systems 20(5):357-403 · February 2003 with 280 Reads
http://kinampark.com/KPTopics/files/Polymers,%20Hydrotropy%20&%20Micelles/2007%20Huh%2C%20Polymeric%20delivery%20systems%20for%20poorly%20soluble%20drugsh.pdf
the aqueous solubility of poorly soluble drugs, and they are usually based on the use of low molecular weight surfactants or their assemblies. Recent advances in polymer science have produced various polymeric systems specifically designed for delivery of poorly sol-uble drugs. Of the many polymeric systems, polymer
https://www.scienomics.com/case-studies/optimizing-drug-and-active-ingredients-release-using-micellar-systems/
Optimizing drug and active ingredients release using micellar systems The main market for delivery systems as studied here is the pharmaceutical industry. Similar interest exists in the Home and Personal care industry and the Food and Flavor industry, where controlled delivery of …
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