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https://thejns.org/focus/view/journals/neurosurg-focus/20/4/foc.2006.20.4.7.xml
Apr 01, 2006 · Convection-enhanced delivery (CED) is the continuous injection under positive pressure of a fluid containing a therapeutic agent. This technique was proposed and introduced by researchers from the US National Institutes of Health (NIH) by the early 1990s to deliver drugs that would otherwise not cross the blood–brain barrier into the parenchyma and that would be too large to diffuse ...Author: Raghu Raghavan, Martin L. Brady, María Inmaculada Rodríguez-Ponce, Andreas Hartlep, Christoph Pedain...
https://www.researchgate.net/publication/7072729_Convection-enhanced_delivery_of_therapeutics_for_brain_disease_and_its_optimization
Convection-enhanced delivery (CED) is the continuous injection under positive pressure of a fluid containing a therapeutic agent.
https://thejns.org/doi/pdf/10.3171/foc.2006.20.4.7
¸Convection-enhanced delivery (CED) is the continuous injection under positive pressure of a fluid containing a ther-apeutic agent. This technique was proposed and introduced by researchers from the US National Institutes of Health (NIH) by the early 1990s to deliver drugs that would otherwise not cross the blood–brain barrier into the parenchyma
https://www.academia.edu/6809735/Convection-enhanced_delivery_of_therapeutics_for_brain_disease_and_its_optimization
Convection-enhanced delivery of therapeutics for brain disease, and its optimization
https://link.springer.com/article/10.1007/s13311-017-0520-4
Mar 15, 2017 · Convection-enhanced delivery (CED) is a promising technique that generates a pressure gradient at the tip of an infusion catheter to deliver therapeutics d It addresses and offers solutions to many limitations of conventional techniques, allowing for delivery past the blood–brain barrier in a targeted and safe manner that can achieve therapeutic drug concentrations.Author: A. M. Mehta, A. M. Sonabend, J. N. Bruce
http://www.aetna.com/cpb/medical/data/700_799/0731.html
Convection-enhanced delivery (CED) is a method of directly administering drugs into the brain in order to enhance the distribution of drugs throughout the brain parehcyma. It involves the stereotactic placement through cranial burr holes of several catheters into brain parenchyma and the subsequent infusion of antineoplastic agents or other therapeutic agents via a microinfusion pump.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117126/
Convection enhanced delivery (CED) is emerging as a promising infusion toolto facilitate delivery of therapeutic agents into the brain via mechanically controlled pumps. Infusion protocols and catheter design have an important impact on delivery.Author: Gurwattan Miranpuri, Angelica Hinchman, Anyi Wang, Dominic Schomberg, Ken Kubota, Martin Brady, Ragh...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657605/
Convection-enhanced delivery to brain parenchyma Accessibility of pharmacological agents from the bloodstream to the CNS meets with a formidable obstacle in the form of the BBB [ 1 ]. There is an absence of direct intracranial administration-only agents that are actively transported through the BBB or that are otherwise permeable through the barrier, which can directly kill tumor cells.Author: Waldemar Debinski, Stephen B Tatter
https://www.sciencedirect.com/science/article/pii/S0967586811001391
Convection-enhanced delivery (CED) is a promising neurosurgical technique for the delivery of potential therapeutic agents to the Parkinson’s disease (PD)-affected striatum. CED utilises stereotactic insertion of a catheter to the striatum and continuous infusion to distribute agents in the brain …Author: Miu Fei Lam, Miu Fei Lam, Meghan G. Thomas, Meghan G. Thomas, Christopher R.P. Lind, Christopher R.P...
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