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https://www.ncbi.nlm.nih.gov/pubmed/19168213
Convection-enhanced delivery of nanocarriers for the treatment of brain tumors. Allard E(1), Passirani C, Benoit JP. Author information: (1)INSERM, U646, Université d'Angers, 10 …Author: Emilie Allard, Catherine Passirani, Jean-Pierre Benoit
https://www.sciencedirect.com/science/article/pii/S014296120900009X
Primary brain tumors have a significant infiltrative capacity as their reappearance after resection usually occurs within 2 cm of the tumor margin. Local delivery method such as Convection-Enhanced Delivery (CED) has been introduced to avoid this recurrence by delivering active molecules via …Author: Emilie Allard, Catherine Passirani, Jean-Pierre Benoit
https://www.researchgate.net/publication/222087912_Convection-enhanced_delivery_of_nanocarriers_for_the_treatment_of_brain_tumors
Convection-enhanced delivery of nanocarriers for the treatment of brain tumors Article · Literature Review in Biomaterials 30(12):2302-2318 · April 2009 with 126 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657605/
The brain is highly accessible for nutrients and oxygen, however delivery of drugs to malignant brain tumors is a very challenging task. Convection-enhanced delivery (CED) has been designed to overcome some of the difficulties so that pharmacological agents that would not normally cross the BBB can be used for treatment.Author: Waldemar Debinski, Stephen B Tatter
https://www.researchgate.net/publication/38013930_Convection-enhanced_delivery_for_the_treatment_of_brain_tumors
The brain is highly accessible for nutrients and oxygen, however delivery of drugs to malignant brain tumors is a very challenging task. Convection-enhanced delivery (CED) has been designed to ...
https://www.sciencedirect.com/science/article/pii/S246845111730048X
Nanocarriers provide controlled delivery of therapeutic and imaging agents for the treatment of brain tumors. • Convection-enhanced delivery (CED) of nanocarriers can significantly enhance intracranial distribution of agents. • Modification of the nanocarrier surface with specific features can enhance diffusion and influence cellular ...Author: Young-Eun Seo, Tom Bu, W. Mark Saltzman
https://link.springer.com/article/10.1007/s13311-017-0520-4
Mar 15, 2017 · Convection-enhanced delivery (CED) is a promising technique that generates a pressure gradient at the tip of an infusion catheter to deliver therapeutics directly through the interstitial spaces of the central nervous system. It addresses and offers solutions to many limitations of conventional techniques, allowing for delivery past the blood–brain barrier in a targeted and safe manner that ...Author: A. M. Mehta, A. M. Sonabend, J. N. Bruce
https://www.deepdyve.com/lp/elsevier/convection-enhanced-delivery-of-nanocarriers-for-the-treatment-of-GCP1ENERw0
Apr 01, 2009 · Convection-enhanced delivery of nanocarriers for the treatment of brain tumors Convection-enhanced delivery of nanocarriers for the treatment of brain tumors Allard, Emilie; Passirani, Catherine; Benoit, Jean-Pierre 2009-04-01 00:00:00 Primary brain tumors have a significant infiltrative capacity as their reappearance after resection usually occurs within 2 cm of the tumor margin.
http://europepmc.org/abstract/MED/19168213
May 01, 2009 · Primary brain tumors have a significant infiltrative capacity as their reappearance after resection usually occurs within 2cm of the tumor margin. Local delivery method such as Convection-Enhanced Delivery (CED) has been introduced to avoid this recurrence by delivering active molecules via positive-pressure methods.Author: Emilie Allard, Catherine Passirani, Jean-Pierre Benoit
https://pubs.acs.org/doi/abs/10.1021/nn503735w
Inhibition of MGMT using O6-benzylguanine (BG) has shown promise in these patients, but its clinical use is hindered by poor pharmacokinetics that leads to unacceptable toxicity. To improve BG biodistribution and efficacy, we developed superparamagnetic iron oxide nanoparticles (NP) for targeted convection-enhanced delivery (CED) of BG to GBM.Author: Zachary R. Stephen, Forrest M. Kievit, Omid Veiseh, Peter A. Chiarelli, Chen Fang, Chen Fang, Kui Wa...
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