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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215502/
Feb 07, 2010 · Introduction. Targeted drug delivery into the colon is highly desirable for local treatment of a variety of bowel diseases such as ulcerative colitis, Crohn’s disease, amebiosis, colonic cancer, local treatment of colonic pathologies, and systemic delivery of protein and peptide drugs.1, 2 The colon specific drug delivery system (CDDS) should be capable of protecting the drug en route to the ...Author: Anil K. Philip, Betty Philip
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508299/
Jun 13, 2015 · The development of colon-targeted oral drug delivery systems has gained increasing interest among formulation scientists in recent years. As discussed above, colon-specific drug delivery systems provide significant therapeutic benefits to the patients in terms of …Author: Seth Amidon, Jack E. Brown, Vivek S. Dave
https://www.researchgate.net/publication/232040952_Oral_colon-specific_drug_delivery_A_review
Two important therapeutic applications which can be found for oral colon-specific drug delivery are the treatment of local disorders of the colon and the delivery of protein and peptide drugs via ...
https://onlinelibrary.wiley.com/doi/abs/10.1002/star.201900262?af=R
In this study, novel enzymatically modified resistant starch type III (EM‐RSIII) derived drug loaded microspheres were developed, for oral colon‐specific delivery of Ciprofloxacin HCl, used as a mo...Author: Anum Khan, Amna Bibi, Huma Ali, Asim. ur. Rehman, Maimoona Qindeel, Muhammad Irfan, Aamer Ali Shah, ...
https://www.slideshare.net/GajananSanap/colon-targeted-drug-delivery-systems
Feb 27, 2016 · 2 In vivo methods: Animal models Rats, mice, pigs and dogs animal models were reported for colon targeted drug delivery systems. For simulating the human physiological environment of the colon, appropriate animal model selection is depends on its approach and design of system. For example, guinea pigs have glycosidase and glucuronidase ...
https://link.springer.com/article/10.1208%2Fs12249-015-0350-9
Jun 13, 2015 · Colon-specific drug delivery systems (CDDS) are desirable for the treatment of a range of local diseases such as ulcerative colitis, Crohn’s disease, irritable bowel syndrome, chronic pancreatitis, and colonic cancer. In addition, the colon can be a potential site for the systemic absorption of several drugs to treat non-colonic conditions.Author: Seth Amidon, Jack E. Brown, Vivek S. Dave
https://www.slideshare.net/bharathpharmacist/colon-specific-drug-delivery-system-39685838
Sep 30, 2014 · Colon specific drug delivery systems: a review on primary and novel approaches by Threveen challa, vinay vynala, Colon specific drug delivery system : A Review on the pharmaceutical approaches with current trends by Cherukuri sowmya. Colon targeted drug delivery system – A Novel perspective by Bhushan Prabhakar Kolte
https://www.researchgate.net/publication/304716338_colon_specific_drug_delivery
Review on, colon specific drug delivery Strategies and in-vitr o in-vivo. evaluation . Harish Gopinath. 1, RajeswariKola Kapudasi. 1 ... colon-specific oral drug delivery systems.Author: Debjit Bhowmik
https://www.sciencedirect.com/science/article/pii/0168365992900694
Initiai studies on colon-specific drug delivery using drug glycosides were, however, performed in the rat. It was found that dexa- methasone could be delivered to the large intes- tine of rats via its glycoside prodrug when ad- ministered orally by gastric intubation [18,19].Author: David R. Friend, Thomas N. Tozer
https://www.japsonline.com/admin/php/uploads/363_pdf.pdf
Keywords: Colon specific drug delivery, pH sensitive, time controlled dependent, microbially d and osmotically controlled system. INTRODUCTION Drug delivery to the colon should be capable of protecting the drug en route to the colon i.e. drug release and absorption should not occur in the stomach as well as the small intestine and
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