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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853346/
Feb 12, 2007 · Therefore, coated microneedles are most suitable for potent drugs, such as therapeutic proteins, DNA and vaccines. Vaccine delivery using coated microneedles is especially attractive, because microneedle-based delivery to the skin can target dendritic cells residing in the epidermis for a more potent immune response.Author: Harvinder S. Gill, Mark R. Prausnitz
https://www.sciencedirect.com/science/article/pii/S0168365917304881
2.6. Transdermal drug delivery in vitro. The coated polymer MNs (5 × 5 arrays, 650-μm height) were applied to the porcine cadaver skin (Pel-Freez, Rogers, AR) to evaluate the insertion and drug delivery efficiency in vitro, with IACUC approval using a house-made applicator. Before the test, the porcine cadaver skin was pretreated, including ...Author: Yang Chen, Bo Zhi Chen, Qi Lei Wang, Xuan Jin, Xin Dong Guo
http://drugdelivery.chbe.gatech.edu/Papers/2007/Gill%20J%20Control%20Release%202007.pdf
Coated microneedles for transdermal delivery Harvinder S. Gilla, Mark R. Prausnitza,b,⁎ a Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA b School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA Received 7 August 2006; accepted 18 October 2006
https://www.sciencedirect.com/science/article/pii/S0168365906005839
Therefore, coated microneedles are most suitable for potent drugs, such as therapeutic proteins, DNA and vaccines. Vaccine delivery using coated microneedles is especially attractive, because microneedle-based delivery to the skin can target dendritic cells residing in …Author: Harvinder S. Gill, Mark R. Prausnitz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695830/
Nov 05, 2015 · Drug administration via the transdermal route is an evolving field that provides an alternative to oral and parenteral routes of therapy. Several microneedle (MN) based approaches have been developed. Among these, coated MNs (typically where drug is deposited ...Author: Rita Haj-Ahmad, Hashim Khan, Muhammad Sohail Arshad, Muhammad Sohail Arshad, Manoochehr Rasekh, Amja...
https://www.researchgate.net/publication/315591197_Fabrication_of_coated_polymer_microneedles_for_transdermal_drug_delivery
These results demonstrated that the coated polymer MN was a safe and effective method for transdermal drug delivery. ... Fabrication of coated polymer microneedles for transdermal drug delivery ...
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