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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998643/
This is a detailed review that highlights the theoretical consider ations of drug delivery, the impact of delivery on drug discovery and development for brain cancers, and current approaches to enhance drug delivery to tumor.Author: Jaishri Blakeley
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629063/
Apr 05, 2014 · Brain tumor-targeted drug delivery systems, which increase drug accumulation in the tumor region and reduce toxicity in normal brain and peripheral tissue, are a promising new approach to brain tumor treatments. Since brain tumors exhibit many distinctive characteristics relative to tumors growing in peripheral tissues, potential targets based ...Author: Xiaoli Wei, Xishan Chen, Man Ying, Weiyue Lu
https://www.nature.com/articles/s41467-019-13198-y
Nov 15, 2019 · The penetration 10 of the released drugs into brain tissues should be high for treatment of infiltrated tumor cells. Local drug delivery to brain tumors without unwanted release to cerebrospinal ...Author: Jongha Lee, Hye Rim Cho, Gi Doo Cha, Hyunseon Seo, Hyunseon Seo, Seunghyun Lee, Chul Kee Park, Jin W...
https://www.sciencedirect.com/science/article/pii/S2211383514000288
In this review, we briefly describe physiological and pathological conditions of brain tumors, including blood–brain/brain tumor barriers, tumor microenvironment and tumor stem cells; we review the corresponding targeting delivery strategies and introduce a systematic targeted drug delivery strategy to overcome current challenges.Author: Xiaoli Wei, Xishan Chen, Man Ying, Weiyue Lu
http://www.cbtddc.org/cbtdd-consortium.aspx
Children's Brain Tumour Drug Delivery Consortium Do you want to improve the outlook for children with brain cancer? If so, and you have an interest in drug delivery approaches, join us.
https://www.sciencedaily.com/releases/2019/12/191203102011.htm
Dec 03, 2019 · Improving drug delivery for brain tumor treatment: Scientists propose combining ultrasound with other techniques to improve drug transport …
https://braintumorcenter.ucsf.edu/research/drug-delivery
One area of active drug delivery research at UCSF involves the development and improvement of convection-enhanced delivery (CED), an experimental technique for directly infusing drugs into a brain tumor. With CED, a small hole is made in the patient’s skull to insert a cannula (a thin tube) that extends to the site of the tumor.
https://www.curetoday.com/articles/new-drug-delivery-method-may-help-fight-aggressive-brain-tumor
Oct 16, 2018 · Children who suffer from a highly aggressive and deadly type of brain tumor may have new hope when it comes to treatment options. Researchers from Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine, both in New York City, tested an approach that appears to be safe and effective at distributing a drug throughout diffuse intrinsic pontine gliomas (DIPG), a tumor …
https://www.sciencedirect.com/book/9780128122181/nanotechnology-based-targeted-drug-delivery-systems-for-brain-tumors
The disrupted vasculature in brain tumor and how novel drug delivery facilitates entry of chemotherapeutic drugs to target site for enhancement of therapeutic effects of drugs have become a major area of today’s research. Among various available drug delivery tools, carbon nanotubes (CNTs) have emerged as promising systems owing to their ...
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