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https://www.sciencedirect.com/science/article/abs/pii/S0168365901002942
The aim of this paper was to evaluate the potential of chitosan nanoparticles as carriers for the anthracycline drug, doxorubicin (DOX). The challenge was to entrap a cationic, hydrophilic molecule into nanoparticles formed by ionic gelation of the positively charged polysaccharide chitosan.Author: Kevin A. Janes, Marie P. Fresneau, Ana Marazuela, Angels Fabra, Marı́a José Alonso
https://www.ncbi.nlm.nih.gov/pubmed/11516503
Jun 15, 2001 · The aim of this paper was to evaluate the potential of chitosan nanoparticles as carriers for the anthracycline drug, doxorubicin (DOX). The challenge was to entrap a cationic, hydrophilic molecule into nanoparticles formed by ionic gelation of the positively charged polysaccharide chitosan.Author: Kevin A. Janes, Marie P. Fresneau, Ana Marazuela, Angels Fabra, Marı́a José Alonso
https://www.sciencedirect.com/science/article/pii/S0144861716302570
Chitosan-based nanoparticles as drug delivery systems for doxorubicin: Optimization and modelling 1. Introduction. Drug delivery systems consist in a controlled release system,... 2. Experimental. All the chemical reagents used in this research work were... 3. Results and discussion. Chitosan Mw ...Author: Paula I.P. Soares, Ana Isabel Sousa, Jorge Carvalho Silva, Isabel M.M. Ferreira, Carlos M.M. Novo, J...
https://www.ncbi.nlm.nih.gov/pubmed/27178936
Aug 20, 2016 · In the present work, two drug delivery systems were produced by encapsulating doxorubicin into chitosan and O-HTCC (ammonium-quaternary derivative of chitosan) nanoparticles. The results show that doxorubicin release is independent of the molecular weight and is higher at acidic pH (4.5) than at physiological pH.Author: Paula I.P. Soares, Ana Isabel Sousa, Jorge Carvalho Silva, Isabel M.M. Ferreira, Carlos M.M. Novo, J...
https://www.researchgate.net/publication/299758913_Chitosan-based_nanoparticles_as_drug_delivery_systems_for_doxorubicin_Optimization_and_modelling
Alternative delivery system basedon chitosan nanoparticles provided loading of up to 70% of doxorubicin (Soares et al., 2016), whereas delivery system based on modified single-walled carbon ...
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