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https://www.hindawi.com/journals/jnm/2012/372725/abs/
Chitosan Nanoparticles as a Percutaneous Drug Delivery System for Hydrocortisone Hydrocortisone (HC) has formed the mainstay for the management of atopic dermatitis.Author: Haliza Katas, Zahid Hussain, Tay Chai Ling
https://www.hindawi.com/journals/jnm/2012/372725/fig3/
Chitosan Nanoparticles as a Percutaneous Drug Delivery System for Hydrocortisone Figure 3 FT-IR spectra of (a) LMwt CS (b) pure HC and (c) HC-loaded LMwt CS NPs (CS 0.2% w/v, HC 1 …
https://www.academia.edu/21789702/Chitosan_Nanoparticles_as_a_Percutaneous_Drug_Delivery_System_for_Hydrocortisone
Chitosan Nanoparticles as a Percutaneous Drug Delivery System for Hydrocortisone
https://core.ac.uk/display/112071936
Hydrocortisone (HC) has formed the mainstay for the management of atopic dermatitis. Hence, HC-loaded chitosan nanoparticles were prepared by ionic crosslinking of high, low molecular weight chitosan (HMwt, LMwt CS) and N-trimethyl chitosan (TMC) with tripolyphosphate. HC loading into CS nanoparticles was confirmed by FT-IR.Author: Haliza Katas, Zahid Hussain and Tay Chai Ling
https://www.cell.com/heliyon/fulltext/S2405-8440(19)31154-5
May 15, 2019 · Chitosan, a natural carbohydrate polymer, has long been investigated for drug delivery and medical applications due to its biodegradability, biocompatibility and low toxicity. The micro/nanoparticulate forms of chitosan are reported to enhance the efficiency of drug delivery with better physicochemical properties including improved solubility and bioavailability. This polymer is …Author: Nazrul Islam, Isra Dmour, Mutasem O Taha
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631287/
A few examples of topically applied, chitosan-based nanoparticle systems are given below. Kim et al. 41 encapsulated retinol, a vitamin A derivative in chitosan nanoparticles. The encapsulation of retinol in chitosan nanoparticles minimized the irritation and toxicity of retinol, and the retinol-loaded chitosan nanoparticles can be potentially used for acne and anti-wrinkle treatment.Author: Zheng Zhang, Pei-Chin Tsai, Tannaz Ramezanli, Bozena B. Michniak-Kohn
https://www.sciencedirect.com/science/article/pii/S0022354915311904
The aim of this study to administer hydrocortisone (HC) percutaneously in the form of polymeric nanoparticles (NPs) to alleviate its transcutaneous absorption, and to derive additional wound-healing benefits of chitosan.Author: Zahid Hussain, Haliza Katas, Mohd Cairul Iqbal Mohd Amin, Endang Kumulosasi, Shariza Sahudin
https://www.sciencedirect.com/science/article/pii/S0378517313000513
In addition, percutaneous delivery offers several advantages over conventional oral or intravenous drug preparations, such as avoiding first pass metabolism and minimizing pain (Barry, 2001). The foremost layer of the skin, the stratum corneum (SC), acts as a major barrier and limits the delivery of most drugs (Moser et al., 2001).Author: Zahid Hussain, Haliza Katas, Mohd Cairul Iqbal Mohd Amin, Endang Kumolosasi, Fhataheya Buang, Shariz...
http://core.ac.uk/display/28769434
Chitosan Nanoparticles as a Percutaneous Drug Delivery System for Hydrocortisone By Tay Chai Ling, Zahid Hussain and Haliza Katas No static citation data No static citation data CiteAuthor: Tay Chai Ling, Zahid Hussain and Haliza Katas
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160948/
Aug 10, 2011 · Such peculiarity of lecithin-chitosan nanoparticles could improve accumulation of quercetin in the epidermis and avoid its permeation through the skin, which indicates that the lecithin-chitosan nanoparticles are an ideal carrier for the cutaneous delivery of quercetin to exert its antioxidant and anti-inflammatory effects in the skin.Author: Qi Tan, Weidong Liu, Chenyu Guo, Guangxi Zhai
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