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https://www.sciencedirect.com/science/article/pii/S0939641112001038
Due to its nontoxic character, permeation enhancing properties, and physicochemical characteristics, chitosan is a suitable material for the design of ocular drug delivery systems. Chitosan-based formulations used for ophthalmic drug delivery are hydrogels , nanoparticles , and coated colloidal systems . Chitosan-based systems have the ...Author: Andreas Bernkop-Schnürch, Sarah Dünnhaupt
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090273/
Apr 11, 2011 · Chitosan nanoparticles are good drug carriers because of their good biocompatibility and biodegradability, and can be readily modified. As a new drug delivery system, they have attracted increasing attention for their wide applications in, for example, ...Author: Jun Jie Wang, Zhao Wu Zeng, Ren Zhong Xiao, Tian Xie, Guang Lin Zhou, Xiao Ri Zhan, Shu Ling Wang
https://www.researchgate.net/publication/260378681_Applications_of_Chitosan_Nanoparticles_in_Drug_Delivery
This has prompted accelerated research activities worldwide on chitosan micro and nanoparticles as drug delivery vehicles[17] [18] [19][20]all class of bioactive molecules. In view of the recent ...
https://www.mdpi.com/journal/pharmaceutics/special_issues/chitosan_drug_delivery
Chitosan is widely available commercially in various forms, and its chemistry lends itself to functionalization. Due to its excellent biocompatibility, biodegradability and versatility, chitosan has been applied to diverse drug delivery systems for nearly every route of administration.
https://pubs.acs.org/doi/10.1021/bm060065f
Several novel functionalized graft copolymer nanoparticles consisting of chitosan (CS) and the monomer methyl methacrylate (MMA), N-dimethylaminoethyl methacrylate hydrochloride (DMAEMC), and N-trimethylaminoethyl methacrylate chloride (TMAEMC), which show a higher solubility than chitosan in a broader pH range, have been prepared by free radical polymerization. The nanoparticles were ...Author: Feng Qian, Fuying Cui, Jieying Ding, Cui Tang, Chunhua Yin
https://www.sciencedirect.com/science/article/pii/S1021949814001410
In this review, we summarize the physicochemical and drug delivery properties of chitosan, selected studies on utilization of chitosan and chitosan-based nanoparticle composites in various drug delivery systems, and selected studies on the application of chitosan films …Author: M.Abd Elgadir, Md.Salim Uddin, Sahena Ferdosh, Aishah Adam, Ahmed Jalal Khan Chowdhury, Md.Zaidul Is...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426784/
More research needs to be conducted on these topics for the rational design of the next generation of oral chitosan drug and gene delivery systems. However, the studies above indicate the feasibility of using chitosan nanoparticles to deliver poorly bioavailable drugs or to achieve in vivo gene expression.Author: Katherine Bowman, Kam W Leong
https://www.cell.com/heliyon/fulltext/S2405-8440(19)31154-5
May 15, 2019 · Chitosan, a natural carbohydrate polymer, has long been investigated for drug delivery and medical applications due to its biodegradability, biocompatibility and low toxicity. The micro/nanoparticulate forms of chitosan are reported to enhance the efficiency of drug delivery with better physicochemical properties including improved solubility and bioavailability. This polymer is known to …Author: Nazrul Islam, Isra Dmour, Mutasem O Taha
https://www.researchgate.net/publication/230559444_Chitosan_nanoparticles_as_a_drug_delivery_system
Chitosan nanoparticles as a drug delivery system. ... Chitosan nanoparticles are good drug carriers because of their good biocompatibility and biodegradability, and can be readily modified.
https://chitolytic.com/crosslinked-chitosan-nanoparticles/
Particulate chitosan structures are 3D crosslinked networks where polymeric chains are interconnected by crosslinkers. The main parameter, which determines the properties of a crosslinked NP, such as drug release and mechanical strength, is the crosslinking density.17 Depending on the desired chitosan structural characteristics, nanoparticles are prepared mainly by four mechanisms:
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