Cell-Permeable Peptides As Delivery Vehicles For Biology And Medicine

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Cell-penetrating peptides as delivery vehicles for biology ...

    https://pubs.rsc.org/en/content/articlelanding/2008/ob/b719950c
    Cell-penetrating peptides (CPPs) have found numerous applications in biology and medicine since the first synthetic cell-permeable sequence was identified two decades ago. Numerous types of drugs have been transported into cells using CPPs, including small-molecule pharmaceuticals, therapeutic proteins, and antisense oligonucleotides.Improved agents for medical imaging have been generated by ...Author: Kelly M. Stewart, Kristin L. Horton, Shana O. Kelley

Cell-penetrating peptides as delivery vehicles for biology ...

    https://www.semanticscholar.org/paper/Cell-penetrating-peptides-as-delivery-vehicles-for-Stewart-Horton/f13b56af6e35643b20abb7229992a3063f5cdf18
    Cell-penetrating peptides (CPPs) have found numerous applications in biology and medicine since the first synthetic cell-permeable sequence was identified two decades ago. Numerous types of drugs have been transported into cells using CPPs, including small-molecule pharmaceuticals, therapeutic proteins, and antisense oligonucleotides. Improved agents for medical imaging have been generated by ...

Cell-penetrating peptides as delivery vehicles for biology ...

    https://www.semanticscholar.org/paper/Cell-penetrating-peptides-as-delivery-vehicles-for-Stewart-Horton/f13b56af6e35643b20abb7229992a3063f5cdf18/figure/1
    Cell-penetrating peptides (CPPs) have found numerous applications in biology and medicine since the first synthetic cell-permeable sequence was identified two decades ago. Numerous types of drugs have been transported into cells using CPPs, including small-molecule pharmaceuticals, therapeutic proteins, and antisense oligonucleotides.

ChemInform Abstract: Cell-Penetrating Peptides as Delivery ...

    https://www.researchgate.net/publication/5291920_ChemInform_Abstract_Cell-Penetrating_Peptides_as_Delivery_Vehicles_for_Biology_and_Medicine
    Cell-penetrating peptides (CPPs) are a family of short cationic peptides that have been employed as delivery vehicles for a good number of small molecules [34] and macromolecules (e.g., antibodies ...

Cell-penetrating peptide - Wikipedia

    https://en.wikipedia.org/wiki/Cell-penetrating_peptide
    Cell-penetrating peptides (CPP) are able to transport different types of cargo molecules across plasma membrane; thus, they act as molecular delivery vehicles. They have numerous applications in medicine as drug delivery agents in the treatment of different diseases including cancer and virus inhibitors, as well as contrast agents for cell ...

Cell Penetrating Peptide for Drug Delivery Products

    https://www.biosyn.com/catalog-peptides/cell-penetrating-peptide-for-drug-delivery.aspx#!
    Cell-penetrating peptides as delivery vehicles for biology and medicine, Org Biomol Chem., 6(13), 2242-55. ... Cell permeable peptides (CPPs) are carriers with small peptide domains that can freely cross cell membranes. ... Cell-penetrating peptides as delivery vehicles for biology and medicine, Org Biomol Chem., 6(13), 2242-55. 4.

Design of a novel cell-permeable chimeric peptide to ...

    https://www.nature.com/articles/s41598-018-34684-1
    Nov 02, 2018 · Biological membranes are impermeable to almost all compounds having a molecular weight greater than 500 Da. Recently, cell penetrating peptides (CPPs) as …Author: Mareike Horn, Ines Neundorf

Vectorial delivery of macromolecules into cells using ...

    https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(00)01520-1
    The ability to direct the import of therapeutic agents into cells and target them to specific organelles would greatly enhance their functional efficacy. The available spectrum of peptide-based import signals and intracellular routing signals might provide practical solutions towards achieving a guided or vectorial delivery of molecules.Author: Jean Gariépy, Kim Kawamura

Biomolecules Free Full-Text Intracellular Delivery of ...

    https://www.mdpi.com/2218-273X/10/2/217
    Cellular uptake and intracellular release efficiency of biomacromolecules is low because of hurdles in the cell membrane that result in limited access to intra-cellular targets with few functional effects. Cell-penetrating peptides (CPPs) act as cargo delivery vehicles to promote therapeutic molecule translocation. Here, we describe the novel CPP-Dot1l that not only penetrates by itself, but ...Author: Jingping Geng, Xiangli Guo, Lidan Wang, Richard Q. Nguyen, Fengqin Wang, Changbai Liu, Hu Wang

Mitochondria-Penetrating Peptides: Chemistry & Biology

    https://www.cell.com/cell-chemical-biology/fulltext/S1074-5521(08)00126-9
    Apr 21, 2008 · Mitochondria are important targets for cancer chemotherapy and other disease treatments. Gaining access to this organelle can be difficult, as the inner membrane is a barrier limiting diffusive transport. A mitochondrial molecular carrier would be a boon to the development of organelle-specific therapeutics. Here, we report a significant advance in the development of mitochondrial transporters ...Author: Kristin L. Horton, Kelly M. Stewart, Sonali B. Fonseca, Qian Guo, Shana O. Kelley

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