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https://www.researchgate.net/publication/11184116_Bone_Morphogenetic_Protein_Delivery_Systems
A review was conducted. To review the rationale for the use of carrier systems to deliver bone morphogenetic proteins to sites of orthopedic repair, and to discuss commonly used carriers.
https://www.ncbi.nlm.nih.gov/pubmed/12205414
Aug 15, 2002 · Bone morphogenetic protein delivery systems. Seeherman H(1), Wozney J, Li R. Author information: (1)Wyeth Research, Cambridge, Massachusetts 02140, USA. STUDY DESIGN: A review was conducted. OBJECTIVES: To review the rationale for the use of carrier systems to deliver bone morphogenetic proteins to sites of orthopedic repair, and to discuss ...Author: Howard Seeherman, John Wozney, Rebecca Li
https://www.ncbi.nlm.nih.gov/pubmed/30883942
OBJECTIVES: This 12-week clinical trial evaluated efficacy and adverse events for two recombinant human bone morphogenetic protein-2 (rhBMP-2) delivery systems in alveolar ridge preservation. MATERIALS AND METHODS: Sixty-four patients had a single tooth that required replacement with an implant, surrounded by > 50% alveolar bone height.
https://journals.lww.com/spinejournal/Fulltext/2002/08151/Bone_Morphogenetic_Protein_Delivery_Systems.5.aspx
Rationale for the Osteogenic Factor Delivery Systems. The rationale for the use of osteogenic factors and associated delivery systems can differ relative to the augmentation of fracture repair in terms of segmental bone loss and spine fusion. 8,48,53,74 Although most fractures heal spontaneously, this process does not appear to be optimized. More rapid and larger callus formation, leading to ...
http://medicalpolicy.bluekc.com/MedPolicyLibrary/Surgery/Standard%20Surgery/05-19_7_Bone_Morphogenetic_Protein.pdf
family. At present, some 20 bone morphogenetic proteins have been identified, all with varying degrees of tissue-stimulating properties. The recombinant human bone morphogenetic proteins (rhBMPs) are delivered to the bone grafting site as part of a surgical procedure; a variety of carrier and delivery systems has been investigated.
https://en.wikipedia.org/wiki/BMP2_(gene)
Bone morphogenetic protein 2 is shown to stimulate the production of bone. [14] [15] Recombinant human protein (rhBMP-2) is currently available for orthopaedic usage in the United States . [16] Implantation of BMP-2 is performed using a variety of biomaterial carriers ("metals, ceramics, polymers, and composites" [17] ) and delivery systems ...
https://www.sciencedirect.com/science/article/pii/S0142961220301551
Local delivery of bone morphogenetic protein-2 from near infrared-responsive hydrogels for bone tissue regeneration. ... Tetracycline-dependent systems, which rely on transactivators regulated by tetracycline or its analog doxycycline, are examples of inducible systems used …Author: Silvia Sanchez-Casanova, Silvia Sanchez-Casanova, Francisco M. Martin-Saavedra, Francisco M. Martin-...
https://providers.bcidaho.com/resources/pdfs/medical-management/Medical%20Policy%20PDF/7%20-%20Surg/07.01.100_04-18-19.pdf
BONE MORPHOGENETIC PROTEIN AND CARRIER AND DELIVERY SYSTEMS Bone morphogenetic proteins are members of the transforming growth factors family. At present, some 20 bone morphogenetic proteins have been identified, all with varying degrees of tissue-stimulating properties. The recombinant human bone morphogenetic proteins (rhBMPs) are delivered ...
https://www.sciencedirect.com/science/article/pii/S0168365914003654
Modulating hydrogel crosslink density and degradation to control bone morphogenetic protein delivery and in vivo bone formation. Author links open overlay panel Julianne L. Holloway Henry Ma Reena Rai Jason A. Burdick. ... R. LiBone morphogenetic protein delivery systems.Author: Julianne L. Holloway, Henry Ma, Reena Rai, Jason A. Burdick
http://europepmc.org/abstract/MED/12205414
Sep 01, 2002 · SUMMARY OF BACKGROUND DATA:Carriers for bone morphogenetic protein in spine fusion are used to increase the retention of these osteogenic factors at the treatment site, and to serve as an osteoconductive matrix for bone forming cells while maintaining a space or volume in which bone formation can occur.Author: Howard Seeherman, John Wozney, Rebecca Li
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