Aptamer Based Drug Delivery

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Aptamers for Targeted Drug Delivery - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033951/
    This proof-of-principle study demonstrated that an anti-TN-C aptamer could be used to target tumors (glioma, breast, and colon) that express high level of TN-C and that aptamers, in general, may have pharmacologic properties that make them excellent agents for tumor-specific drug delivery.Author: Partha Ray, Rebekah R. White

Aptamers based drug delivery - LinkedIn SlideShare

    https://www.slideshare.net/AnuragPandey60/aptamers-based-drug-delivery-93903621
    Apr 15, 2018 · aptamers based drug delivery 1. aptamer based drug delivery presented by :- anurag pandey (m.pharm) department of pharmaceutics, institute of pharmacy, nirma university, ahemdabad under the guidance of dr. tejal mehta (hod) department of pharmaceutics, institute of pharmacy, nirma university, ahemdabad 2.

Multifunctional aptamer-based nanoparticles for targeted ...

    https://www.sciencedirect.com/science/article/pii/S014296121630028X
    Multifunctional aptamer-based nanoparticles for targeted drug delivery to circumvent cancer resistance. Author links open overlay panel Juan Liu a 1 Tuo Wei a 1 Jing Zhao a Yuanyu Huang b Hua Deng a Anil Kumar a Chenxuan Wang a Zicai Liang b Xiaowei Ma a Xing-Jie Liang a. Show more.Author: Juan Liu, Tuo Wei, Jing Zhao, Yuanyu Huang, Hua Deng, Anil Kumar, Chenxuan Wang, Zicai Liang, Xiaowe...

Molecular aptamers for drug delivery - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218254/
    Because each type of nanomaterial has different optical, electrochemical, and mechanical properties, medical diagnostic and drug delivery agents with diverse characteristics can be used for different applications, moving aptamer-based nanomedicine closer to reality.Author: Weihong Tan, Weihong Tan, Hui Wang, Yan Chen, Yan Chen, Yan Chen, Xiaobing Zhang, Haizhen Zhu, Chaoy...

Molecular aptamers for drug delivery

    https://tan.chem.ufl.edu/wp-content/uploads/sites/39/pubs/important-articles/Molecular%20aptamers%20for%20drug%20delivery.pdf
    Molecular aptamers for drug delivery Weihong 3 Tan1,2, Hui Wang2, Yan Chen1,2,3, Xiaobing Zhang1, Haizhen Zhu1, ... aptamer-based anti-VEGF treatment for age-related ... Aptamers for drug delivery Target name Aptamer Selection technique Delivery application Refs Epidermal growth factor receptor (EGFR) RNA Purified extracellular domain of EGFR ...

Aptamer-Based Tumor-Targeted Drug Delivery for ...

    https://pubs.acs.org/doi/10.1021/nn901374b
    DNA-based aptamer fails as a simultaneous cancer targeting agent and drug delivery vehicle for a phenanthroline-based platinum(II) complex. Journal of Inorganic Biochemistry 2013, 128, 124-130. DOI: 10.1016/j.jinorgbio.2013.07.021.Author: Yen-An Shieh, Shu-Jyuan Yang, Ming-Feng Wei, Ming-Jium Shieh

Aptamer-guided nanomedicines for anticancer drug delivery ...

    https://www.sciencedirect.com/science/article/pii/S0169409X18302473
    Other nanocarriers investigated for aptamer-guided drug delivery and/or imaging include metal- and silica-based nanoparticles. Although their biodegradation and toxicity profile may raise concerns, they allow a degree of control of their physicochemical properties that is sometimes not possible with the aforementioned organic or biomimetic ...Author: Walhan Alshaer, Walhan Alshaer, Hervé Hillaireau, Elias Fattal

Precision-Guided Missile-Like DNA Nanostructure Containing ...

    https://pubs.acs.org/doi/10.1021/jacs.9b09782
    Precision-Guided Missile-Like DNA Nanostructure Containing Warhead and Guidance Control for Aptamer-Based Targeted Drug Delivery into Cancer Cells in Vitro and in Vivo. Changhe Ouyang. Changhe Ouyang. Cancer Metastasis Alert and Prevention Center, Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, National ...Author: Changhe Ouyang, Songbai Zhang, Songbai Zhang, Songbai Zhang, Chang Xue, Xin Yu, Huo Xu, Zhenmeng Wan...

Aptamer Based Targeted Drug Delivery Systems: Current ...

    https://www.researchgate.net/publication/328159638_Aptamer_Based_Targeted_Drug_Delivery_Systems_Current_Potential_and_Challenges
    Therefore, aptamers can be served as ideal targeting ligands for drug delivery. Since their excellent properties, different aptamer-mediated drug delivery systems had been developed for cancer ...

Aptamers as targeted therapeutics: current potential and ...

    https://www.nature.com/articles/nrd.2016.199
    Nov 03, 2016 · Nucleic acid aptamers offer several advantages over traditional antibodies, but their clinical translation has been delayed by several factors, including insufficient potency, lack of …Author: Jiehua Zhou, John Rossi

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