We have collected information about Antibody Targeted Drug Delivery for you. Follow the links to find out details on Antibody Targeted Drug Delivery.
https://www.sciencedirect.com/science/article/pii/S136759311000075X
The underlying reason for this has been obtained in pre-clinical biodistribution and pharmacokinetics studies showing that targeted delivery leads to high intratumoral free drug concentrations, while non-target tissues are largely spared from chemotherapeutic exposure.Author: Stephen C Alley, Nicole M Okeley, Peter D Senter
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023511/
Apr 26, 2016 · INTRODUCTION. Targeted drug delivery systems have several advantages over traditional systems, including more safe movement through the cell membrane, reduced side effects and a higher efficiency (1–3).Antibody molecules, which specifically react with particular antigens on the cell surface, can serve as appropriate targeting elements/carriers for targeted drug delivery.Author: Yaghoub Safdari, Vahideh Ahmadzadeh, Masoumeh Khalili, Hossein Zarei Jaliani, Vahid Zarei, Vahid Erf...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944323/
Antibody–drug conjugates (ADCs), a potent class of anticancer therapeutics, comprise a high-affinity antibody (Ab) and cytotoxic payload coupled via a suitable linker for selective tumor cell killing. ... ADCs are an emerging class of targeted anticancer drug delivery agent that confer selective and sustained cytotoxic drug delivery to tumors .Author: Samaresh Sau, Hashem O. Alsaab, Hashem O. Alsaab, Sushil Kumar Kashaw, Sushil Kumar Kashaw, Katyayan...
https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-5-70
Nov 09, 2012 · In parallel to naked TMAs, antibody-drug conjugates (ADCs) have been developed for targeted delivery of potent anti-cancer drugs with the aim of bypassing the morbidity common to conventional chemotherapy.Author: Michael A Firer, Gary Gellerman
https://www.researchgate.net/publication/297283078_Targeted_Drug_Delivery_A_Review
Targeted drug delivery, also known as smart drug delivery, is a method of treatment that involves the increase in medicament in one or few body parts in comparison to others. Two strategies are
https://www.sciencedirect.com/science/article/abs/pii/S0165247817301761
Targeted drug delivery by nanomaterials is an effective anti-cancer therapeutic approach. Abstract. Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made these approaches non-effective in the significant number of patients. Non ...Author: Behdokht Bahrami, Behdokht Bahrami, Mohammad Hojjat-Farsangi, Mohammad Hojjat-Farsangi, Hamed Mohamm...
https://www.nature.com/articles/nrd1957
Jan 20, 2006 · Here, we discuss recent preclinical and clinical data for antibody–drug conjugates and fusion proteins with a special focus on drug components …Author: David Schrama, Ralph A. Reisfeld, Jürgen C. Becker
https://www.vaxiion.com/rbmc-targeted-drug-delivery.html
Vaxiion has developed several methods of converting recombinant bacterial minicells (rBMCs) into targeted drug delivery products. In general, these can be separated into two basic targeting strategies; non-antibody-based targeting & antibody-based targeting approaches.
https://molmed.biomedcentral.com/articles/10.2119/molmed.2016.00043
Apr 26, 2016 · Targeted drug delivery systems have several advantages over traditional systems, including more safe movement through the cell membrane, reduced side effects and a higher efficiency (1–3).Antibody molecules, which specifically react with particular antigens on the cell surface, can serve as appropriate targeting elements/carriers for targeted drug delivery.Author: Yaghoub Safdari, Vahideh Ahmadzadeh, Masoumeh Khalili, Hossein Zarei Jaliani, Vahid Zarei, Vahid Erf...
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