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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177684/
DRUG DELIVERY WITH VIRUS-BASED NANOPARTICLES. The development of VNPs that target specific cell types has allowed for the addition of toxic payloads by conjugation, infusion, and/or encapsulation so that the target cells are killed, thus allowing the selective elimination of cancer cells, or other diseased cells, without off-target effects.Author: Kristopher J. Koudelka, Andrzej S. Pitek, Marianne Manchester, Nicole F. Steinmetz
https://www.sciencedirect.com/science/article/pii/S0169409X12000087
New nanocarrier platforms based on natural biological building blocks offer great promises in revolutionalizing medicine. The usage of specific protein cage structures: virus-like particles (VLPs) for drug packaging and targetted delivery is summarized here.Author: Y. Ma, Y. Ma, R.J.M. Nolte, Jeroen Johannes Lambertus Maria Cornelissen
https://www.ncbi.nlm.nih.gov/pubmed/29869258
We describe methods to transform TMV rods to spheres, load TMV rods and spheres with the chemotherapeutic drug, doxorubicin (DOX), to deliver modified particles to breast cancer cells, and to determine the IC50 values of the plant virus-based drug delivery system. PMID: 29869258 [Indexed for MEDLINE] Publication Types:Author: Michael A. Bruckman, Anna E. Czapar, Nicole F. Steinmetz
https://www.researchgate.net/publication/221785164_Virus-based_nanocarriers_for_drug_delivery
Virus-based nanocarriers for drug delivery. ... researchers to utilize virus-like nanoparticles in targeted delivery of genes in gene therapy, as there is a possibility of using virus-like ...
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