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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · INTRODUCTION. Basically gene therapy is an intracellular delivery of genomic materials (transgene) into specific cells to generate a therapeutic effect by correcting an existing abnormality or providing the cells with a new function.[] Different types of gene delivery systems may be applied in gene therapy to restore a specific gene function or turning off a special gene(s).
https://link.springer.com/article/10.2165%2F00003088-200241120-00001
Sep 13, 2012 · This manuscript will discuss the viral-based subset of current gene transfer vectors. In particular, the most established viral vectors to date, including parvovirus, adenovirus, retro-virus, lentivirus, and herpesvirus-based vectors, are described, as well as the current innovative improvements being made to each.Author: Cathryn Mah, Barry J. Byrne, Terence R. Flotte
https://www.youtube.com/watch?v=5Ryb7ZLJSh0
Dec 09, 2013 · This gene therapy video tutorial will talk about different gene delivery systems available to deliver normal copy of gene inside host tissue. For more inform...Author: Shomu's Biology
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417261/
Mar 12, 2019 · Viral vectors based on DNA for gene delivery systems . Viral vectors based on DNA for gene delivery are usually longer lasting and integrating into the genomes. DNA-based viral vectors are lentivirus, poxvirus, adenovirus, adeno-associated virus, retrovirus, human foamy virus (HFV) and herpes virus . DNA-based viral vectors for gene delivery ...Author: YK Sung, SW Kim
https://www.sciencedirect.com/science/article/pii/S0142961218302862
Nevertheless, with the rapid development of various synthetic vectors, non-viral vectors are very likely to provide unique advantages over viral vectors in these fields. Here, we review recent advances of non-viral vectors for CRISPR/Cas9 delivery in vivo and focus on those non-viral delivery systems applied for CRISPR/Cas9-based gene therapy.Author: Ling Li, Ling Li, Shuo Hu, Xiaoyuan Chen
https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/gene-delivery-systems-recent-progress-in-viral-and-non-viral-therapy
Current gene delivery systems are divided into three categories: viral-based, non-viral based, and combined hybrid systems. Viral gene delivery systems consist of viruses that are modified to be replication-deficient which can deliver genes to the target cells to provide expression.Author: Erdal Cevher, Ali Demir Sezer, Emre Şefik Çağlar
https://www.nature.com/articles/gt20175
Jan 17, 2017 · Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems. ... A defective nontransmissible recombinant Sendai virus …Author: S Guan, J Rosenecker
https://link.springer.com/article/10.1023%2FA%3A1007548826495
Feb 01, 2000 · Gene transfer to humans requires carriers for the plasmid DNA which canefficiently and safely carrythe gene into the nucleus of the desired cells. A series of chemically differentcationic polymers arecurrently being investigated for these purposes. Although many cationic polymersindeed condense DNAspontaneously, which is a requirement for gene transfer in most types of cells,the ...Author: Stefaan C. De Smedt, Joseph Demeester, Wim E. Hennink
https://www.takarabio.com/learning-centers/gene-function/viral-transduction/recombinant-virus-comparison
However, selecting the best viral gene delivery system for your experimental aim can be challenging. Use the tables below to compare the characteristics of lentivirus, retrovirus, adenovirus, and adeno-associated virus (AAV), and select the best viral transduction system for your experiment.
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