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https://www.slideshare.net/Aparajitha_Anne/gene-delivery-system
May 19, 2012 · Non-Viral delivery Systems:Non-viral delivery system has some advantages over viral system. Non-viralare simple and safer alternative for the viral systems and low hostimmunogenicity will be two. 18. Naturally Occurring compounds:It is simplest method of injecting naked DNA into the human body i.e. it alsocalled Naked DNA.
https://www.slideshare.net/SalmanHashmi10/gene-therapy-and-gene-delivery-systems
Dec 19, 2014 · Gene therapy and gene delivery systems 1. GENES • Are carried on a chromosome • The basic unit of heredity • Encode how to make a protein • DNA …
https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
The main limitation of non-viral systems is their low transfection efficiency, although it has been improved by different strategies and the efforts are still ongoing ; actually, advances of non-viral delivery have lead to an increased number of products entering into clinical trials. However, viral vector has dominated the clinical trials in ...Author: Alicia Rodríguez Gascón, Ana del Pozo-Rodríguez, María Ángeles Solinís
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · INTRODUCTION. Basically gene therapy is an intracellular delivery of genomic materials (transgene) into specific cells to generate a therapeutic effect by correcting an existing abnormality or providing the cells with a new function.[] Different types of gene delivery systems may be applied in gene therapy to restore a specific gene function or turning off a special gene(s).
https://cdn.intechopen.com/pdfs/40265/InTech-Gene_delivery_systems_recent_progress_in_viral_and_non_viral_therapy.pdf
Viral-mediated gene delivery systems consist of viruses that are modified to be replication-deficient, but which can deliver DNA for expression. Adenoviruses, retroviruses, and lentiviruses are used as viral gene-delivery vectors (Escors and Breckpot, 2010). Non-viral gene delivery systems were introduced as an alternative to viral-based systems.
https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/gene-delivery-systems-recent-progress-in-viral-and-non-viral-therapy
Viral-mediated gene delivery systems consist of viruses that are modified to be replication-deficient, but which can deliver DNA for expression. Adenoviruses, retroviruses, and lentiviruses are used as viral gene-delivery vectors (Escors and Breckpot, 2010). Non-viral gene delivery systems were introduced as an alternative to viral-based systems.Author: Erdal Cevher, Ali Demir Sezer, Emre Şefik Çağlar
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