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https://pubs.acs.org/doi/abs/10.1021/mp060098%2B
Vaccine Delivery Methods Using Viral Vectors. View Author Information. Swedish Institute for Infectious Disease Control and Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 82 Stockholm, Sweden, and Carolina Vaccine Institute, University of North Carolina, Chapel Hill, North Carolina 27599-7292. Cite This:Mol.Author: Andreas Bråve, Karl Ljungberg, Britta Wahren, Margaret A. Liu
https://www.ncbi.nlm.nih.gov/pubmed/17274663
Vaccine delivery methods using viral vectors. Bråve A(1), Ljungberg K, Wahren B, Liu MA. Author information: (1)Swedish Institute for Infectious Disease Control and Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 82 Stockholm, Sweden.Author: Andreas Bråve, Karl Ljungberg, Britta Wahren, Margaret A. Liu
https://www.researchgate.net/publication/6529381_Vaccine_Delivery_Methods_Using_Viral_Vectors
One of the limitations of viral vectors for DNA vaccine or gene therapy applications is their induction of antibodies against the viral vector itself or the existence of pre-existing antibodies against the viral vectors, which nullify the effect of the viral vectors after a few doses [34, 35].
https://www.sciencedirect.com/science/article/pii/S0024320520302988
Another important strategy in virus mediated vaccine delivery is the viral vector-DC vaccine, virus vector-Car T. Targeting transgene expression to dendritic cells (DCs) has become a promising approach for guiding the immune system towards immunity or tolerance.Author: Balamurugan Shanmugaraj, Lohanathan Bharathi Priya, B. Mahalakshmi, Shanmugam Subbiah, Rouh-Mei Hu, ...
https://www.who.int/biologicals/publications/trs/areas/vaccines/typhus/viral_vectors/en/
Vaccines based on viral vectors Much progress has been made towards the development of novel vaccines and vaccination approaches. Viral vectors have been studied as potential tools to deliver vaccines as they present advantages over traditional vaccines in that they stimulate a broad range of immune responses including cell mediated immunity.
https://www.hindawi.com/journals/jir/2019/8303648/
Given these and the ability of LAB to elicit a specific immune response against recombinant foreign antigens, these bacteria have been considered potential candidates as mucosal vaccine vectors. This delivery system can confer protection against antigen degradation and, thanks to its uptake at the GIT level, can activate both innate and adaptive immune responses [78, 79].Author: E. Criscuolo, V. Caputo, V. Caputo, R. A. Diotti, R. A. Diotti, G. A. Sautto, G. A. Kirchenbaum, N. ...
https://www.nature.com/articles/nrmicro2240
Dec 07, 2009 · Recombinant viruses can act as vaccine vectors by mediating the delivery of antigens from other infectious agents to a host.Author: Simon J. Draper, Jonathan L. Heeney
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494222/
Jul 29, 2014 · Viral vectors are promising tools for gene therapy and vaccines. Viral vector-based vaccines can enhance immunogenicity without an adjuvant and induce a robust cytotoxic T lymphocyte (CTL) response to eliminate virus-infected cells.Author: Takehiro Ura, Kenji Okuda, Masaru Shimada
https://www.mdpi.com/2076-393X/4/2/9/htm
Some modes of delivery include, adjuvants (aluminum hydroxide, Ribi formulation, QS21), liposomes, nanoparticles, virus like particles, immunostimulatory complexes (ISCOMs), dendrimers, viral vectors, DNA delivery via gene gun, electroporation or Biojector 2000, cell penetrating peptides, dendritic cell receptor targeting, toll-like receptors, chemokine receptors and bacterial toxins.Author: Vasso Apostolopoulos
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