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https://www.news-medical.net/health/Vaccine-Delivery.aspx
Jun 05, 2019 · Vaccine administration has been traditionally via injections but several new methods of vaccine delivery are also being explored these days. These new methods are hoped to …
https://www.nature.com/articles/nrd.2017.243
Jan 12, 2018 · mRNA vaccines represent a promising alternative to conventional vaccine approaches, but their application has been hampered by instability and delivery …
https://www.who.int/immunization/programmes_systems/supply_chain/optimize/TS_opt_trends_vac_avail.pdf
• Vaccine manufacturers are conservative, and the majority of existing and new vaccines will continue to be delivered by needle and syringe unless incentives and or data are generated to support alternative delivery methods. • A wide range of novel vaccine technologies, many …
https://www.sciencedirect.com/science/article/pii/S0264410X16309173
A quadrivalent vaccine containing VLPs of types 6, 11, 16 and 18 produced in yeast with an aluminium hydroxyphosphate sulphate adjuvant • A bivalent vaccine containing recombinant baculovirus produced HPV 16 & 18 VLPs with aluminium hydroxide + 3-O-de-acylated-4-mono-phosphoryl lipid A (MPL) adjuvant (ASO4).
https://www.researchgate.net/profile/Heather_Benson2/publication/301780335_Transdermal_Delivery_of_Vaccines/links/572abdec08aef7c7e2c4fe45/Transdermal-Delivery-of-Vaccines.pdf
and development of transdermal delivery of vaccines. The skin as a site of vaccine delivery, its barrier properties and the approaches to ... free immunization methods has thus become an important ...
https://www.who.int/bulletin/volumes/89/3/10-079426/en/
In this case, delivery of a 20% intradermal dose with either needle and syringe or disposable-syringe jet injectors could result in cost savings of 71–73% per immunized child. 33. In applications where it is warranted, significant investment by vaccine manufacturers and other stakeholders will be required to change the route of vaccine delivery.
https://www.cdc.gov/vaccines/pubs/pinkbook/safety.html
Printer friendly version pdf icon [16 pages]. Vaccine safety is a prime concern for the public, manufacturers, immunization providers, and recipients of vaccines. This chapter describes how vaccines licensed for use in the United States are monitored for safety, and presents general information about the provider’s role in immunization safety.
https://academic.oup.com/jid/article/216/suppl_1/S273/3935035
A structured questionnaire was designed based on the study objectives to assess different RI components as implemented under BPHS, including vaccine availability, cold-chain management, service delivery, microplanning, and social mobilization, as well as documentation.
https://en.wikipedia.org/wiki/DNA_vaccination
DNA vaccination is a technique for protecting against disease by injection with genetically engineered plasmid containing the DNA sequence encoding the antigen(s) against which an immune response is sought so cells directly produce an antibody, producing a protective immunological response. DNA vaccines have potential advantages over conventional vaccines, including the ability to induce a ...
https://www.historyofvaccines.org/timeline/all
The middle of the 20 th century was an active time for vaccine research and development. Methods for growing viruses in the laboratory led to rapid discoveries and innovations, including the creation of vaccines for polio. ... with recombinant DNA technology and new delivery techniques leading scientists in new directions. ... This timeline ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182663
From 2012 to 2016, Gavi, the Vaccine Alliance, provided support for countries to conduct small-scale demonstration projects for the introduction of the human papillomavirus vaccine, with the aim of determining which human papillomavirus vaccine delivery strategies might be effective and sustainable upon national scale-up. This study reports on the operational costs and cost determinants of ...
http://www.pitt.edu/~super7/32011-33001/32171.ppt
DNA vaccines Traditional vaccines HOW DNA VACCINE IS MADE Viral gene Expression plasmid Plasmid with foreign gene Recombinant DNA Technology Bacterial cell Transform into bacterial cell Plasmid DNA Plasmid DNA get Amplified Plasmid DNA Purified Ready to use METHODS OF DELIVERY Syringe delivery:- Either intramuscularly or Intradermally Contd..
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Each method has advantages and disadvantages, and not all methods can be used for every medication. Improving current delivery methods or designing new ones can enhance the use of existing medications. Dime-sized patch of dissolvable microneedles for self-administration of influenza vaccine. Credit: Georgia Tech.
https://www.vaccines.gov/basics/types
There are several different types of vaccines. Each type is designed to teach your immune system how to fight off certain kinds of germs — and the serious diseases they cause. When scientists create vaccines, they consider: How your immune system responds to the germ Who needs to be vaccinated against the germ The best technology or approach to create the vaccine Based on a number of these ...
https://jamanetwork.com/journals/jama/fullarticle/2676502
Other examples of vaccine platform technologies include viral vector–based approaches where genes encoding viral proteins are incorporated into viral vectors (eg, adenovirus, poxvirus, vesicular stomatitis virus, or paramyxovirus vectors) for gene-based immunogen expression and delivery, or chimeric replication-competent viruses in which the vaccine antigens of one virus are expressed in a ...
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