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https://www.tandfonline.com/doi/abs/10.1517/17425241003677731
Jul 26, 2016 · The ability to control the delivery of drugs from implanted materials is difficult to achieve, but offers promise in diverse areas such as infection-resistant medical devices and responsive implants for diabetics.Areas covered in this review: This review gives a broad overview of recent progress in the use of triggers that can be used to achieve modulation of drug release rates from implantable biomaterials.Author: Colin P McCoy, Christopher Brady, John F Cowley, Seana M McGlinchey, Niamh McGoldrick, Deborah J Kin...
https://www.ncbi.nlm.nih.gov/pubmed/20205603
TAKE HOME MESSAGE: The use of externally or internally applied triggers of drug delivery to biomaterials has significant potential for improved delivery modalities and infection resistance.Author: Colin P McCoy, Christopher Brady, John F Cowley, Seana M McGlinchey, Niamh McGoldrick, Deborah J Kin...
https://www.researchgate.net/publication/41806244_Triggered_drug_delivery_from_biomaterials
The use of externally or internally applied triggers of drug delivery to biomaterials has significant potential for improved delivery modalities and infection resistance.
https://www.ncbi.nlm.nih.gov/pubmed/29986234
The NIR-triggered release behavior of Sr2+ by flawing the PLGA shells is investigated and the microspheres exhibit excellent cell viability and biodegradability. Implantation of the BP-SrCl2/PLGA microspheres into a rat femoral defect demonstrates good tissue compatibility and excellent bone regeneration capacity under NIR light irradiation.Author: Xuzhu Wang, Xuzhu Wang, Jundong Shao, Mustafa Abd El Raouf, Mustafa Abd El Raouf, Hanhan Xie, Hao Hu...
https://www.onlinelibrary.wiley.com/doi/full/10.1002/adma.201705328
Advances in biomaterials for drug delivery are enabling significant progress in biology and medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists, and clinicians generate innovative strategies and materials to treat a range of diseases.Author: Owen S. Fenton, Katy N. Olafson, Padmini S. Pillai, Michael J. Mitchell, Robert Langer
https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201901489
Most notably, the extremely limited cellular uptake of PEGylated nanoparticles hinders efficient intracellular drug delivery to cancer cells. 11 To overcome this PEG dilemma, stimuli‐responsive dePEGylation of nanoparticles within the target tumor has been investigated. 12, 13 In the majority of cases, dePEGylation is triggered by an endogenous stimuli (low pH, 14 matrix metalloproteinases …Author: Li Kong, Quanchi Chen, Frederick Campbell, Ewa Snaar‐Jagalska, Alexander Kros
https://www.sciencedirect.com/science/article/pii/S014296121630672X
Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells Author links open overlay panel R. Brad Jones a b c Stephanie Mueller a c Sudha Kumari a c Vlad Vrbanac a d Shy Genel e Andrew M. Tager a Todd M. Allen a Bruce D. Walker a …Author: R. Brad Jones, R. Brad Jones, R. Brad Jones, Stephanie Mueller, Stephanie Mueller, Sudha Kumari, Sud...
https://www.pharmaceutical-journal.com/research/perspective-article/using-smart-biomaterials-and-systems-for-targeted-drug-delivery/11121790.fullarticle
Microbubbles have exemplified one of the drug delivery systems being investigated. This dosage form comprises elastic and compressible units that have a much lower density than water. They reflect ultrasound and lower the threshold for cavitation, which creates small …
https://www.biomaterials.org/sigs-and-committees-sigs-and-committees-overview/drug-delivery
The Drug Delivery Special Interest Group will deal with the science and technology of controlled release of active agents from delivery systems. Controlled drug release is achieved by the use of diffusion, chemical reactions, dissolutions or osmosis, used either singly or in combination.
https://www.nature.com/articles/natrevmats201720
May 09, 2017 · These drug delivery systems are constructed from materials that are sensitive to a wide range of external stimuli, including light, ultrasound, electrical and magnetic fields, and specific molecules. The responsiveness conferred by these materials allows the release of therapeutics to be triggered on demand and remotely by a physician or patient.Author: Yanfei Wang, Daniel S. Kohane
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