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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517817/
Nov 01, 2012 · We speculated the increased drug delivery in the first case was due to intravascular release during peak plasma concentrations of liposomal drug. This result led to the current hypothesis: The mechanism of drug delivery from Dox-TSL + heat is due to perivascular drug penetration as a result of rapidly triggered intravascular liposomal drug ...Author: Ashley A. Manzoor, Lars H. Lindner, Chelsea D. Landon, Ji-Young Park, Andrew J. Simnick, Matthew R. ...
https://www.nature.com/articles/ncomms4364
Mar 11, 2014 · Stimuli-triggered drug delivery systems have been increasingly used to promote physiological specificity and on-demand therapeutic efficacy of anticancer drugs. Here we …Author: Ran Mo, Ran Mo, Tianyue Jiang, Tianyue Jiang, Rocco DiSanto, Wanyi Tai, Zhen Gu
http://www.eurekaselect.com/140894/article
Background: Smart triggered release in controlled drug delivery has met an astonishing interest from the scientific community in the past few years due to the obvious medical benefits this type of systems represents. The reduction in toxicity due to a non-systemic administration is not the only reason for this increase, although it is a major ...
https://www.nature.com/articles/natrevmats201720
May 09, 2017 · Drug delivery systems that are externally triggered to release drugs and/or target tissues hold considerable promise for improving the treatment of …Author: Yanfei Wang, Daniel S. Kohane
http://www.ibme.ox.ac.uk/research/non-invasive-therapy-drug-delivery/triggered-drug-release
See also enhanced drug delivery. Release Mechanisms. Release of the drug may be induced by exposing the vehicles to various external stimuli. The majority of the research currently being conducted in BUBBL is focused on the use of ultrasound to trigger release through: Generation of heat to activate thermally sensitive carriers.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889806/
The enzyme-based strategies are particularly interesting as they require no prior knowledge of the tumour localization. The basis of this review is an evaluation of the current status of drug delivery strategies focused on triggered drug release by disease-associated enzymes.
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30332-2/fulltext
Aug 01, 2018 · To our knowledge, this clinical study is the first to investigate the safety and feasibility of extracorporeally triggered drug release in oncology and to quantify the potential benefits of this approach in terms of the drug dose, distribution, and cellular delivery, in addition to radiologically assessing the observed therapeutic response ...Author: Paul C Lyon, Paul C Lyon, Paul C Lyon, Michael D Gray, Christophoros Mannaris, Lisa K Folkes, Michae...
https://pubs.acs.org/doi/abs/10.1021/bm2009125
Aug 24, 2011 · Spatio-temporal control strategy of drug delivery systems based nano structures. Journal of Controlled Release 2017, 255, 176-201. DOI: 10.1016/j.jconrel.2017.04.003. Yanmei Yang, Jing Mu, Bengang Xing. Photoactivated drug delivery and bioimaging.Author: Qiao Jin, Fabian Mitschang, Seema Agarwal
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