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https://www.sciencedirect.com/science/article/pii/S0169409X01001934
Oct 31, 2001 · Currently, the treatment of posterior segment disease is limited by the difficulty in delivering effective doses of drugs to target tissues in the posterior vitreous, retina or choroid. The traditional topical route of ophthalmic drug delivery does not yield therapeutic drug levels in the posterior tissues of the eye.Author: Dayle H Geroski, Henry F Edelhauser
https://www.sciencedirect.com/science/article/abs/pii/S0169409X01001934
Exciting new treatments are being developed for retinal degenerations and posterior segment eye disease. The successful treatment of these visually devastating diseases will likely require delivering effective doses of pharmacologic agents to the posterior segment, possibly in conjunction with surgical or genetic interventions.Author: Dayle H Geroski, Henry F Edelhauser
https://www.ncbi.nlm.nih.gov/pubmed/11672874
Oct 31, 2001 · Transscleral drug delivery for posterior segment disease. Geroski DH(1), Edelhauser HF. Author information: (1)Department of Ophthalmology, Emory Eye Center, Suite B2600, 1365B Clifton Road, NE, Atlanta, GA 30322, USA. Exciting new treatments are being developed for retinal degenerations and posterior segment eye disease.Author: Dayle H Geroski, Henry F Edelhauser
https://www.researchgate.net/publication/328150640_Transscleral_Drug_Delivery_to_Retina_and_Posterior_Segment_Disease
Request PDF Transscleral Drug Delivery to Retina and Posterior Segment Disease The complexities of the anatomical and physiological barriers pose a challenge for the treatment of posterior ...
https://www.researchgate.net/publication/11679480_Transcleral_drug_delivery_for_posterior_segment_disease
Drug delivery to the posterior segment is a greater challenge and currently the standard route is via intravitreal (IVT) injection, notwithstanding the risks of endophthalmitis and retinal ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839363/
Feb 01, 2010 · Treatment of diseases of the posterior segment of the eye, such as age-related macular degeneration, cytomegalovirus retinitis, diabetic retinopathy, posterior uveitis and retinitis pigmentosa, requires novel drug delivery systems that can overcome the many barriers for efficacious delivery of therapeutic drug concentrations.Author: Shalin S Shah, Lori Vidal Denham, Jasmine R Elison, Partha S Bhattacharjee, Christian Clement, Tashf...
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