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https://www.sciencedirect.com/science/article/pii/S0378517301008274
Although ketoprofen has a short elimination half-life of 1.5–4 h after oral administration (Jamali and Brocks, 1990), its plasma levels were maintained relatively consistent for ∼24 h after transdermal application . Thus, transdermal delivery of ketoprofen may …Author: Yun-Seok Rhee, Jung-Gyo Choi, Eun-Seok Park, Sang-Cheol Chi
https://patents.google.com/patent/US7989496B2/en
A topical or transdermal composition including a polar derivative of ketoprofen and a pharmaceutically acceptable topical or transdermal carrier, wherein the polar derivative of ketoprofen comprises a polarity that is greater than that of ketoprofen.Author: Rod Hartwig, David Houze
https://www.hindawi.com/journals/ap/2014/468456/
The aim of the present study was to investigate the nanoemulgel as transdermal delivery system for poorly water soluble drug, ketoprofen, in order to overcome the troubles associated with its oral delivery. Different nanoemulsion components (oil, surfactant, and cosurfactant) were selected on the basis of solubility and emulsification ability.Author: Ritika Arora, Geeta Aggarwal, S. L. Harikumar, Kirandeep Kaur
https://www.ncbi.nlm.nih.gov/pubmed/28163223
Apr 15, 2017 · Comparison of transdermal and oral absorption studies revealed that transdermal administration of ketoprofen with A8 dendrimer showed comparable absorption and plasma drug levels with oral route. The excised mouse skin after in vivo permeation study with dendrimers and ultrasound did not show major toxic reactions.Author: Jyothsna Manikkath, Aswathi R. Hegde, Guruprasad Kalthur, Harendra S. Parekh, Srinivas Mutalik
https://www.ncbi.nlm.nih.gov/pubmed/11576778
Oct 09, 2001 · Transdermal delivery of ketoprofen using microemulsions. Rhee YS(1), Choi JG, Park ES, Chi SC. Author information: (1)College of Pharmacy, Sungkyunkwan University, 440-746, Suwon Kyunggi-Do, South Korea. A transdermal preparation containing ketoprofen was developed using O/W microemulsion system.Author: Yun-Seok Rhee, Jung-Gyo Choi, Eun-Seok Park, Sang-Cheol Chi
https://www.sciencedirect.com/science/article/pii/S0378517317300832
Transdermal delivery, which is one of the most important routes for chronic administration, is the non-invasive method of permeating drugs through the skin for systemic delivery. Transdermal delivery systems can avoid peaks and troughs of drug levels in plasma …Author: Jyothsna Manikkath, Aswathi R. Hegde, Guruprasad Kalthur, Harendra S. Parekh, Srinivas Mutalik
https://www.researchgate.net/publication/11771263_Transdermal_delivery_of_ketoprofen_using_microemulsions
A transdermal preparation containing ketoprofen was developed using O/W microemulsion system. Of the oils tested, oleic acid was chosen as the oil phase of the microemulsion, as it showed a good ...
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