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https://www.sciencedirect.com/science/article/pii/S0169409X18303090
However, effective insulin delivery via the skin remains challenging due to the intrinsic, protective properties of the intact skin. Therapeutics with low molecular weight (<500 Da) can easily penetrate the skin, while the passive transport of protein drugs with higher molecular weight, such as insulin, is significantly restricted [].To overcome skin barriers in transdermal insulin delivery ...Author: Yuqi Zhang, Yuqi Zhang, Jicheng Yu, Anna R. Kahkoska, Jinqiang Wang, Jinqiang Wang, John B. Buse, Zh...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/transdermal-delivery
Anushree Herwadkar, Ajay K. Banga, in Peptide and Protein Delivery, 2011. Transdermal delivery of peptides and proteins is a promising alternative to conventional parenteral delivery. Enhancement techniques such as microporation, iontophoresis, or sonophoresis help bypass penetration barriers of the skin and enable the delivery of hydrophilic molecules and macromolecules.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556146/
Jan 15, 2019 · A transdermal delivery strategy transports insulin across the skin barrier represents a minimally invasive and attractive method for insulin delivery in contrast to painful hypodermic injections [24, 25]. It also has several advantages over oral, pulmonary, and nasal administration techniques.Author: Yuqi Zhang, Yuqi Zhang, Jicheng Yu, Anna R. Kahkoska, Jinqiang Wang, Jinqiang Wang, John B. Buse, Zh...
https://www.researchgate.net/publication/11055498_Iontophoresis-Based_Transdermal_Delivery_Systems
Transdermal iontophoresis is the administration of ionic therapeutic agents through the skin by the application of a low-level electric current.
https://www.deepdyve.com/lp/elsevier/enhancement-of-transdermal-drug-delivery-via-synergistic-action-of-d9XAtaRN3J
Nov 01, 2009 · Read "Enhancement of transdermal drug delivery via synergistic action of chemicals, Biochimica et Biophysica Acta Biomembranes Or Bba Biomembranes" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.researchgate.net/publication/6868485_Effect_of_electroporation_and_pH_on_the_iontophoretic_transdermal_delivery_of_human_insulin
Effect of electroporation and pH on the iontophoretic transdermal delivery of human insulin Article in International Journal of Pharmaceutics 326(1-2):13-9 · January 2007 with 15 Reads
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
INTRODUCTION. The prevalence of diabetes is increasing throughout the world. The International Diabetes Federation estimated 366 million people had diabetes in 2011 and is expected rise to 552 million by 2030.[] Though type 2 diabetes mellitus (T2DM) accounts for 85-95% of diabetes, the prevalence of T1DM has increased by 2-3% in certain parts of Europe and USA.[1,2] Thus, diabetes …
https://link.springer.com/chapter/10.1007/0-306-46803-4_13
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.Author: Jens Brange, Lotte Langkjær
https://www.nature.com/articles/srep07914
Jan 21, 2015 · A patchless dissolving microneedle delivery system enabling rapid and efficient transdermal drug delivery Skip to main content Thank you for visiting nature.com.Author: Shayan F. Lahiji, Manita Dangol, Hyungil Jung
https://link.springer.com/article/10.1007/s11095-016-1885-5
Feb 23, 2016 · In contrast, Chen et al. studied the use of iontophoresis to enhance the transdermal delivery of insulin encapsulated in nanovesicles through holes created in the skin by solid MN arrays . Insulin was encapsulated in nanovesicles prepared using soybean lecithin and propylene glycol.Author: Eneko Larrañeta, Maelíosa T. C. McCrudden, Aaron J. Courtenay, Ryan F. Donnelly
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