Targeted Anticancer Drug Delivery

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Controlled drug delivery vehicles for cancer treatment and ...

    https://www.nature.com/articles/s41392-017-0004-3
    Mar 16, 2018 · The enhanced efficacy of magnetic albumin microspheres in the targeted delivery of an anticancer agent compared to the pure drug in rat model is …Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti

Targeted and controlled anticancer drug delivery and ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753509/
    Targeted and controlled anticancer drug delivery and release with magnetoelectric nanoparticles. ... Targeted drug delivery in cancer therapy. Technology in cancer research & treatment 4, 3636 (2005). Wang A. Z., Langer R. & Farokhzad O. C. Nanoparticle delivery of cancer drugs.Author: Alexandra Rodzinski, Rakesh Guduru, Ping Liang, Ali Hadjikhani, Tiffanie Stewart, Emmanuel Stimphil,...

Modular design of nanobody–drug conjugates for targeted ...

    https://pubs.rsc.org/en/content/articlelanding/2019/cc/c9cc01391a#!
    A multifunctional nanobody–drug conjugate (NDC) was constructed in this work for the targeted delivery of a platinum prodrug and an MRI contrast agent. The NDC can be specifically internalized into EGFR positive cancer cells, resulting in higher therapeutic effect and lower side-effects relative to cisplatin

Multiresponsive Nanogels for Targeted Anticancer Drug Delivery

    https://www.researchgate.net/publication/318294003_Multiresponsive_Nanogels_for_Targeted_Anticancer_Drug_Delivery
    Nanogels with a biomolecular coating (biocoating) were shown to be capable of triggered delivery of anticancer drug Doxorubicin. The biocoating was formed utilizing binding between glycogen and ...

cRGD-functionalized, DOX-conjugated ... - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292876/
    Multifunctional and water-soluble superparamagnetic iron oxide (SPIO) nanocarriers were developed for targeted drug delivery and positron emission tomography/magnetic resonance imaging (PET/MRI) dual-modality imaging of tumors with integrin α v β 3 expression. An anticancer drug was conjugated onto the PEGylated SPIO nanocarriers via pH-sensitive bonds.Author: Xiaoqiang Yang, Hao Hong, Jamison J. Grailer, Ian J. Rowland, Alireza Javadi, Samuel A. Hurley, Yuli...

Targeted and controlled anticancer drug delivery and ...

    https://www.nature.com/articles/srep20867
    Feb 15, 2016 · An important challenge in treating cancer in general is to find a technology for a controlled targeted drug delivery and release to eradicate tumor cells while sparing normal cells.Author: Alexandra Rodzinski, Rakesh Guduru, Ping Liang, Ali Hadjikhani, Tiffanie Stewart, Emmanuel Stimphil,...

Drug Delivery: Multistage pH-Responsive Liposomes for ...

    https://www.researchgate.net/publication/225280473_Drug_Delivery_Multistage_pH-Responsive_Liposomes_for_Mitochondrial-Targeted_Anticancer_Drug_Delivery_Adv_Mater_272012
    Drug Delivery: Multistage pH-Responsive Liposomes for Mitochondrial-Targeted Anticancer Drug Delivery (Adv. Mater. 27/2012) Article in Advanced Materials 24(27):3659-65 · July 2012 with 593 Reads

Hypoxia-targeted drug delivery - Chemical Society Reviews ...

    https://pubs.rsc.org/en/content/articlelanding/2019/cs/c8cs00304a
    Hypoxia-targeted drug delivery . Amit Sharma, † a Jonathan F ... These factors decrease the therapeutic efficacy of anticancer drugs and can provide a barrier to advancing drug leads beyond the early stages of preclinical development. This review highlights various hypoxia-targeted and activated design strategies for the formulation of drugs ...Author: Amit Sharma, Jonathan F. Arambula, Seyoung Koo, Rajesh Kumar, Rajesh Kumar, Hardev Singh, Hardev Sin...

Multistage pH‐Responsive Liposomes for Mitochondrial ...

    https://onlinelibrary.wiley.com/doi/10.1002/adma.201201498
    Multistage pH‐Responsive Liposomes for Mitochondrial‐Targeted Anticancer Drug Delivery. Ran Mo. Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China. Search for more papers by this author.Author: Ran Mo, Qiong Sun, Jingwei Xue, Nan Li, Wenyuan Li, Can Zhang, Qineng Ping

Tumor-specific targeting of an anticancer drug delivery ...

    https://www.pnas.org/content/102/36/12962
    Sep 06, 2005 · The efficacy of cancer chemotherapy is limited by severe adverse side effects induced by anticancer drugs (1-4).The cytotoxic effect on healthy organs can be significantly diminished by employing special drug delivery systems (DDS) targeted specifically to cancer cells (5, 6).Targeting is especially important in circumstances where a localized tumor is removed surgically, and …Author: S. S. Dharap, Y. Wang, P. Chandna, J. J. Khandare, B. Qiu, S. Gunaseelan, P. J. Sinko, S. Stein, A. ...

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