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https://www.medindia.net/news/healthinfocus/new-needle-invented-for-tissue-targeted-drug-delivery-186166-1.htm
An intelligent injector has been developed that allows the safe and effective delivery of drugs to target tissues. This injector, called Intelligent-Injector for Tissue-Targeting (i2T2), has been developed by a group of scientists at the Brigham and Women's Hospital, Boston, Massachusetts, USA. New Needle Invented for Tissue Targeted Drug Delivery.
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1440-1681.1997.tb02708.x
Jun 28, 2007 · Drug delivery through the skin has been used to target the epidermis, dermis and deeper tissues and for systemic delivery. The major barrier for the transport of drugs through the skin is the stratum corneum, with most transport occurring through the intercellular region.Author: Roberts
https://www.sciencedirect.com/science/article/pii/S1369702105710336
The most promising application of in vivo targeted nanoparticle drug delivery currently involves readily accessible targets in the vasculature, such as malignant immune system cells. A second promising application is in local attachment via interventional catheterization procedures to the vasculature or other tissues.Author: Tarek M. Fahmy, Peter M. Fong, Amit Goyal, W. Mark Saltzman
https://www.mdpi.com/1999-4915/12/4/412/htm
This review discusses the recent progress in the development of long-acting and tissue-targeted therapies against HIV for the delivery of direct antivirals, and examines how such developments fit in the context of exploring HIV cure strategies. ... Utilizing a nanotherapeutic drug delivery approach to tissues could potential overcome problems ...
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · Being nanosized, these structures penetrate in the tissue system, facilitate easy uptake of the drug by cells, permit an efficient drug delivery, and ensure action at the targeted location. The uptake of nanostructures by cells is much higher than that of large particles with size ranging between 1 and 10 µm [ 17 , 24 ].Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
In drug delivery research, this means starting with a delivery method. The target may be whole organs (heart, lung, brain), tissue types (muscle, nerve), disease-specific structures (tumor cells…
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
These systems in general can be used to provide targeted (cellular or tissue) delivery of drugs, improve bioavailability, sustain release of drugs or solubilize drugs for systemic delivery. This process can be adapted to protect therapeutic agents against enzymatic degradation (i.e., nucleases and proteases) (Haixiong Ge, 2002). Thus, the advantages of using nanoparticles for drug delivery are a …Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://pubs.acs.org/doi/abs/10.1021/acs.chemrev.7b00013
Sep 12, 2017 · The probability of regulatory approval can conceivably be further enhanced by exploiting the same targeting ligand, conjugated to an imaging agent, to select patients whose diseased tissues display sufficient targeted receptors for therapeutic efficacy.Author: Madduri Srinivasarao, Philip S. Low
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Nanotechnology is a rapidly growing research area in the field of catalysts, biosensors, bioimaging, energy devices, and targeted drug delivery 132,133,134. The …Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
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