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https://www.sciencedirect.com/science/article/pii/S0169409X06001839
3. pH-responsive polymers in drug delivery. The pH is an important signal, which can be addressed through pH-responsive materials. The physiological pH changes have been mentioned earlier . Ionisable polymers with a pK a value between 3 and 10 are candidates for pH-responsive systems . Weak acids and bases like carboxylic acids, phosporic acid ...Author: Dirk Schmaljohann
https://www.researchgate.net/publication/330496117_PH_Responsive_Polymers_in_Drug_Delivery
Stimuli-responsive polymer or 'intelligent' polymer recently emerged as new potential for drug delivery. Some stimuli have been listed such as thermo, light, ultrasound and pH.
https://www.researchgate.net/publication/6672111_Thermo-_and_pH-responsive_polymers_in_drug_delivery
Thermo- and pH-responsive polymers in drug delivery Article · Literature Review in Advanced Drug Delivery Reviews 58(15):1655-70 · January 2007 with 268 Reads How we measure 'reads'
http://www.thno.org/v10p4557.htm
Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications. Theranostics. 2018;8:3038-58 187. Hou SL, Chen SS, Dong Y, Gao S, Zhu BS, Lu QH. Biodegradable cyclomatrix polyphosphazene nanoparticles: a novel pH-responsive drug self-framed delivery system.
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_6/Lecture%206%20References/Schmaljohann%202006.pdf
Thermo- and pH-responsive polymers in drug delivery ... deal with pH-responsive drug delivery system. Thermo-responsive polymer is also covered to a large extent, as well as double-responsive system. The physico-chemical behaviour underlying the phase transition will be discussed
https://pubs.acs.org/doi/abs/10.1021/am400572b
Targeted and efficient delivery of therapeutics to tumor cells is one of the key issues in cancer therapy. In the present work, we report a temperature and pH dual responsive core–shell nanoparticles comprising smart polymer shell coated on magnetic nanoparticles as an anticancer drug carrier and cancer cell-specific targeting agent.Author: Banalata Sahoo, K. Sanjana P. Devi, Rakesh Banerjee, Tapas K. Maiti, Panchanan Pramanik, Dibakar Dha...
https://www.sciencedirect.com/science/article/pii/B9780081019979000059
The DDSs with stimuli-responsive controlled release function hold great potential in clinical applications. There are several types of stimuli-responsive mechanisms using polymers for drug delivery applications as illustrated in Table 5.1. However, this review will only discuss the pH-responsive polymer-based DDSs.Author: Elaref Ratemi
http://onlinelibrary.wiley.com/doi/10.1002/adma.200401057/full
Feb 04, 2005 · Abstract. Novel polymer core–shell nanoparticles that exhibited a pH-dependent lower critical solution temperature (LCST) have been synthesized. The nanoparticles displayed stable structure in a nominal physiological environment but deformed and precipitated in an acidic environment, thereby releasing the enclosed drug molecules (see Figure).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681499/
Jul 12, 2019 · 2.1. Chitosan. Chitosan as a natural stimuli-responsive polymer is capable of showing both thermo-responsive and pH responsive properties [51,52].The drug delivery systems made of chitosan show relevance to drug delivery applications especially for cancer therapy and skin treatment due to their biocompatibility, biodegradability, and low toxicity [].Author: Sudipta Chatterjee, Patrick Chi-leung Hui
https://www.mdpi.com/2073-4360/11/11/1834
This work demonstrates a simple approach for coating a porous polymer layer on stainless-steel (SS) microneedles characterized by a pH-responsive formulation for self-regulated drug delivery. For many drug-delivery applications, the release of therapeutic agents in an acidic microenvironment is desirable. Acid-sensitive polymers and hydrogels were extensively explored, but easily prepared ...Author: Asad Ullah, Haroon Khan, Hye Jin Choi, Gyu Man Kim
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