Targeted Ultrasound Drug Delivery

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Ultrasonic Drug Delivery – A General Review

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/
    Keywords: ultrasound, targeted drug delivery, liposomes, microbubbles, micelles, chemopotentiation, hyperthermia, cavitation, DNA, protein, chemotherapy. 1. Mechanisms of Ultrasonic-Enhanced Drug Delivery. Ultrasound (US) has been employed to enhance the delivery and activity of drugs for the past two decades. In the past 6 years, however ...Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples

Safety and feasibility of ultrasound-triggered targeted ...

    https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30332-2/fulltext
    Aug 01, 2018 · The combined treatment of LTLD and non-invasive focused ultrasound hyperthermia in this study seemed to be clinically feasible, safe, and able to enhance intratumoural drug delivery, providing targeted chemo-ablative response in human liver tumours that were refractory to …Author: Paul C Lyon, Paul C Lyon, Paul C Lyon, Michael D Gray, Christophoros Mannaris, Lisa K Folkes, Michae...

Potential and problems in ultrasound-responsive drug ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635663/
    Apr 22, 2013 · Ultrasound is an important local stimulus for triggering drug release at the target tissue. Ultrasound-responsive drug delivery systems (URDDS) have become an important research focus in targeted therapy. URDDS include many different formulations, such as microbubbles, nanobubbles, nanodroplets, liposomes, emulsions, and micelles.Author: Ying-Zheng Zhao, Li-Na Du, Cui-Tao Lu, Yi-Guang Jin, Shu-Ping Ge

Ultrasound drug delivery - YouTube

    https://www.youtube.com/watch?v=Z6BMYNXbwLU
    Oct 21, 2015 · Using ultrasound waves, researchers have found a way to enable rapid delivery of drugs to the gastrointestinal (GI) tract. This approach could make it …

Closed-loop control of targeted ultrasound drug delivery ...

    https://www.pnas.org/content/114/48/E10281
    Nov 28, 2017 · Focused ultrasound is currently the only method of reversible blood–brain barrier disruption for targeted drug delivery without incision or radiation. A significant …Author: Tao Sun, Tao Sun, Yongzhi Zhang, Chanikarn Power, Phillip M. Alexander, Jonathan T. Sutton, Muna Ary...

Ultrasound releases drug to alter activity in targeted ...

    http://med.stanford.edu/news/all-news/2018/11/ultrasound-releases-drug-to-alter-activity-in-targeted-brain-area.html
    But having crossed this barrier, the drug is quickly soaked up by brain tissue, so that it never gets farther than about a half-millimeter from the capillary where it’s been released. Airan and his colleagues injected these particles intravenously into rats and explored …

Ultrasound-sensitive nanoparticle aggregates for targeted ...

    https://www.sciencedirect.com/science/article/pii/S0142961217303976
    Here we describe injectable, ultrasound (US)-responsive, nanoparticle aggregates (NPAs) that disintegrate into slow-release, nanoscale, drug delivery systems, which can be targeted to selective sites by applying low-energy US locally.Author: Anne-Laure Papa, Netanel Korin, Mathumai Kanapathipillai, Akiko Mammoto, Tadanori Mammoto, Amanda Ji...

Using High-Intensity Focused Ultrasound as a Means to ...

    https://journals.sagepub.com/doi/full/10.1177/8756479316663167
    Aug 16, 2016 · Drug delivery using the thermal effect mechanism uses a focused increase in temperature to release drugs to a targeted location. 9 Hyperthermia can result, which is known to increase cellular uptake of anticancer medications. 9 High-intensity focused ultrasound–induced hyperthermia has shown to significantly enhance the delivery of anticancer ...Author: Ashley McClure

Ultrasound to enhance cancer drug delivery: Sound waves ...

    https://www.sciencedaily.com/releases/2018/03/180320084420.htm
    Mar 20, 2018 · Ultrasound mediated, targeted drug delivery is an emerging therapy approach with great potential and we are delighted to be in the forefront of this development."

Ultrasound and Microbubbles for Targeted Chemotherapy Delivery

    https://www.medgadget.com/2017/08/ultrasound-microbubbles-targeted-chemotherapy-delivery.html
    Researchers in Norway have developed a chemotherapy delivery system consisting of microbubbles containing drug-loaded nanoparticles. When the researchers apply ultrasound to the microbubbles in a ...

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