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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/
Keywords: ultrasound, targeted drug delivery, liposomes, microbubbles, micelles, chemopotentiation, hyperthermia, cavitation, DNA, protein, chemotherapy. 1. Mechanisms of Ultrasonic-Enhanced Drug Delivery. Ultrasound (US) has been employed to enhance the delivery and activity of drugs for the past two decades. In the past 6 years, however ...Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30332-2/fulltext
Aug 01, 2018 · The combined treatment of LTLD and non-invasive focused ultrasound hyperthermia in this study seemed to be clinically feasible, safe, and able to enhance intratumoural drug delivery, providing targeted chemo-ablative response in human liver tumours that were refractory to …Author: Paul C Lyon, Paul C Lyon, Paul C Lyon, Michael D Gray, Christophoros Mannaris, Lisa K Folkes, Michae...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635663/
Apr 22, 2013 · Ultrasound is an important local stimulus for triggering drug release at the target tissue. Ultrasound-responsive drug delivery systems (URDDS) have become an important research focus in targeted therapy. URDDS include many different formulations, such as microbubbles, nanobubbles, nanodroplets, liposomes, emulsions, and micelles.Author: Ying-Zheng Zhao, Li-Na Du, Cui-Tao Lu, Yi-Guang Jin, Shu-Ping Ge
https://www.youtube.com/watch?v=Z6BMYNXbwLU
Oct 21, 2015 · Using ultrasound waves, researchers have found a way to enable rapid delivery of drugs to the gastrointestinal (GI) tract. This approach could make it …
https://www.pnas.org/content/114/48/E10281
Nov 28, 2017 · Focused ultrasound is currently the only method of reversible blood–brain barrier disruption for targeted drug delivery without incision or radiation. A significant …Author: Tao Sun, Tao Sun, Yongzhi Zhang, Chanikarn Power, Phillip M. Alexander, Jonathan T. Sutton, Muna Ary...
http://med.stanford.edu/news/all-news/2018/11/ultrasound-releases-drug-to-alter-activity-in-targeted-brain-area.html
But having crossed this barrier, the drug is quickly soaked up by brain tissue, so that it never gets farther than about a half-millimeter from the capillary where it’s been released. Airan and his colleagues injected these particles intravenously into rats and explored …
https://www.sciencedirect.com/science/article/pii/S0142961217303976
Here we describe injectable, ultrasound (US)-responsive, nanoparticle aggregates (NPAs) that disintegrate into slow-release, nanoscale, drug delivery systems, which can be targeted to selective sites by applying low-energy US locally.Author: Anne-Laure Papa, Netanel Korin, Mathumai Kanapathipillai, Akiko Mammoto, Tadanori Mammoto, Amanda Ji...
https://journals.sagepub.com/doi/full/10.1177/8756479316663167
Aug 16, 2016 · Drug delivery using the thermal effect mechanism uses a focused increase in temperature to release drugs to a targeted location. 9 Hyperthermia can result, which is known to increase cellular uptake of anticancer medications. 9 High-intensity focused ultrasound–induced hyperthermia has shown to significantly enhance the delivery of anticancer ...Author: Ashley McClure
https://www.sciencedaily.com/releases/2018/03/180320084420.htm
Mar 20, 2018 · Ultrasound mediated, targeted drug delivery is an emerging therapy approach with great potential and we are delighted to be in the forefront of this development."
https://www.medgadget.com/2017/08/ultrasound-microbubbles-targeted-chemotherapy-delivery.html
Researchers in Norway have developed a chemotherapy delivery system consisting of microbubbles containing drug-loaded nanoparticles. When the researchers apply ultrasound to the microbubbles in a ...
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