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https://pubs.rsc.org/en/content/articlelanding/2015/cc/c4cc07489k#!
Mesoporous silica coated upconverting nanoparticles are loaded with the anticancer drug doxorubicin and grafted with ruthenium complexes as photoactive molecular valves. Drug release was triggered by 974 nm light with 0.35 W cm−2. Such low light intensity minimized overheating problems …
https://www.sciencedirect.com/science/article/pii/S1748013215000742
The clinical relevance of plasmonic nanoparticles has grown as drug delivery systems based on the fact that gold nanoparticles have moved into clinical trials , , . However, the phototriggerability of these drug delivery systems has not yet been applied in clinical settings.Author: Alina Y. Rwei, Alina Y. Rwei, Weiping Wang, Weiping Wang, Daniel S. Kohane, Daniel S. Kohane
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201300183
Mar 12, 2013 · Photomediated drug release: Silica‐coated upconverting nanoparticles with mesopores modified by azobenzene molecules were synthesized.The azobenzene molecules make possible the release of the anticancer drug doxorubicin from the pore network of the mesoporous silica outer layer by irradiation with near‐infrared (NIR) laser light.Author: Jianan Liu, Wenbo Bu, Limin Pan, Jianlin Shi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071191/
Nanoparticles are widely used as nanocarriers in a drug/gene delivery system due to their long circulation time and low multi-drug resistance. In particular, lanthanide-doped upconversion nanoparticles (UCNPs) that can emit UV and visible light by near-infrared (NIR) upconversion demonstrated more efficient and safer drug/gene delivery.Author: Gibok Lee, Yong Il Park
https://www.acsmaterial.com/materials/quantum-dots-upconverting-nanoparticles/upconverting-nanoparticles-ucnps.html
Upconverting nanoparticles are nanomaterials that can convert near-infrared, low-energy radiations into visible, high-energy radiations via a nonlinear optical process. Our selection of upconverting nanoparticles includes both oil and water dispersible particles. These photoluminescent nanoparticles have a number of applications: Bioimaging.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669578/
Aug 01, 2015 · While light has been used to trigger drug delivery devices of a wide range of sizes [13, 16–20], this article will focus on developments in nanoparticulate photoresponsive drug delivery systems, including phototriggered targeting of and drug release from nanoparticles. We will first discuss some considerations relevant to the clinical ...Author: Alina Y. Rwei, Alina Y. Rwei, Weiping Wang, Weiping Wang, Daniel S. Kohane, Daniel S. Kohane
https://www.sciencedirect.com/science/article/pii/S0169409X12001883
Lanthanide-doped upconverting luminescent nanoparticles (UCNPs) are promising materials for optical imaging-guided drug delivery and therapy due to their unique optical and chemical properties. UCNPs absorb low energy near-infrared (NIR) light and emit high-energy shorter wavelength photons.Author: Jie Shen, Liang Zhao, Gang Han
https://pubs.acs.org/doi/abs/10.1021/am503039f
Aug 04, 2014 · Targeted drug delivery using functional nanoparticles has provided new strategies for improving therapeutic efficacy while concurrently minimizing toxicity. Photodynamic therapy is an approach that offers control of drug delivery by use of an external photon source to allow active therapeutic release to a target area. Upconverting nanoparticles (UCNPs) have potential to operate as …Author: Laura L. Fedoryshin, Anthony J. Tavares, Eleonora Petryayeva, Samer Doughan, Ulrich J. Krull
https://www.researchgate.net/publication/236049438_NIR-Triggered_Anticancer_Drug_Delivery_by_Upconverting_Nanoparticles_with_Integrated_Azobenzene-Modified_Mesoporous_Silica
NIR-Triggered Anticancer Drug Delivery by Upconverting Nanoparticles with Integrated Azobenzene-Modified Mesoporous Silica Article in Angewandte Chemie International Edition 52(16) · April 2013 ...
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