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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Recently, our laboratory has developed XPclad ® nanoparticles that represent a novel formulation method that uses planetary ball milling to generate particles of uniform size (Figure 1), 100% loading efficiency of hydrophobic or hydrophilic drugs, subsequent coating for targeted delivery, and control of LogP for systemic, cutaneous, or oral ...Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Nanoparticles and drug delivery. Drug delivery and related pharmaceutical development in the context of nanomedicine should be viewed as science and technology of nanometer scale complex systems (10–1000 nm), consisting of at least two components, one of which is a pharmaceutically active ingredient (Duncan 2003; Ferrari 2005), although nanoparticle formulations of the drug itself are also ...Author: Wim H De Jong, Paul Ja Borm
https://www.sciencedirect.com/science/article/pii/S0927776520301211
Targeted delivery platforms based on nanoparticles with great advantages including prolonged blood circulation, enhanced intratumoral accumulation, improved anticancer efficacy, and diminished side effects, might lead to great breakthroughs on osteosarcoma chemotherapy [12,13].Author: Xin Huang, Wei Wu, Wenbo Yang, Xiangcheng Qing, Zengwu Shao
https://www.sciencedirect.com/science/article/pii/S0169409X09003238
2.3. Kidney and lung targeted delivery. Kidney-targeted drug delivery is critical when attempting to reduce extra-renal toxicity of the drug and to improve its therapeutic efficiency for diseases occurring at the kidney. It may be particularly beneficial for drugs such as non-steroidal anti-inflammatory drugs (NSAIDS) . The mesangial cells of ...Author: Jae Hyung Park, Gurusamy Saravanakumar, Kwang Meyung Kim, Ick Chan Kwon
https://experiment.com/projects/targeted-drug-delivery-by-using-magnetic-nanoparticles
Atif has been working extensively on Nanoparticles, Spintronics and Targeted Drug Delivery by using Magnetic Nanoparticles so that we can target medicines to act towards specific areas in our body. The patch works by injecting tiny microscopic particles (nanoparticles) into the bloodstream that can pinpoint malignant cancer cells and attach ...
https://pubs.acs.org/doi/abs/10.1021/nn201592s
Chemotherapy is an important modality in cancer treatment. The major challenges of recent works are to improve drug loading, increase selectivity to target cells, and control the precise release of drugs. In the present study, we devised a smart drug carrier, an aptamer/hairpin DNA–gold nanoparticle (apt/hp-Au NP) conjugate for targeted delivery of drugs.Author: Yun-Ling Luo, Yi-Syun Shiao, Yu-Fen Huang
https://www.particle-works.com/applications/targeted-drug-delivery/
Targeted Drug Delivery. Targeted drug delivery is a rapidly developing field within pharmacology. This application involves Active Pharmaceutical Ingredient (API) encapsulation or tethering to nano- or microparticles in order to deliver therapeutic molecules to the malignant site. This is usually undertaken using one of the two targeting ...
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The use of ideal nano-drug delivery system is decided primarily based on the biophysical and biochemical properties of the targeted drugs being selected for the treatment . However, problems such as toxicity exhibited by nanoparticles cannot be ignored when considering the use of nanomedicine.Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
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