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https://www.mdedge.com/familymedicine/article/63401/prophylactic-oxytocin-or-after-placental-delivery
Evidence summary. The prophylactic use of oxytocic drugs reduces the risk of postpartum hemorrhage (PPH) by about 40% and has been widely adopted as a routine policy in the active management of the third stage of labor. 1 A number of studies have evaluated the timing of oxytocin after delivery (). TABLE
https://www.nct.org.uk/labour-birth/your-guide-labour/third-stage-labour-delivering-placenta-and-cord-clamping
What is the third stage of labour? ... Involves an injection of a drug called syntocinon or ergometrine in your thigh soon after your baby’s born. It speeds up the delivery of the placenta – it usually happens within 30 minutes of having your baby. Your midwife will push on your uterus and pull the placenta out by the umbilical cord.
https://www.drugs.com/pro/syntocinon.html
Jun 21, 2019 · Syntocinon ® (oxytocin) injection does not contain the amino acids characteristic of vasopressin, and therefore has fewer and less severe cardiovascular effects. Syntocinon ® (oxytocin) exerts a selective action on the smooth musculature of the uterus, particularly toward the end of pregnancy, during labor and immediately following delivery ...
https://www.mdedge.com/obgyn/article/64781/obstetrics/routine-use-oxytocin-birth-just-right-amount-prevent-postpartum
In the United States, oxytocin is the uterotonic most often administered at birth. It is commonly administered: 1) after delivery of the baby’s anterior shoulder, 2) after delivery of the baby but before delivery of the placenta, or 3) after delivery of the placenta. Of the three options, the last one is …
https://clinicaltrials.gov/ct2/show/NCT03006380
Prophylactic Oxytocin Before Versus After Placental Delivery to Reduce Blood Loss in Vaginal Delivery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
https://www.researchgate.net/publication/12521571_Prophylactic_syntometrine_versus_oxytocin_for_delivery_of_the_placenta_Cochrane_Review
If IV delivery is not possible, IM delivery may be used as this route of delivery did show a benefit to prevent PPH greater than 500 mL and there was a trend to decrease the need for therapeutic ...
https://www.mumsnet.com/Talk/childbirth/719222-Oxytocin-injection-for-placental-delivery
Oxytocin injection for placental delivery (97 Posts) Add message Report. ... Syntocinon has been implicated in cases of retained placenta - once you've given the drug you're on a stopwatch to get the placenta out, and that is often considered to be a Bad Thing. My understanding is that oxytocin in isolation has much less potential for bad ...
http://www.uhs.nhs.uk/birth/the-process/delivery-of-the-placenta/Syntocinon/Syntocinon.aspx
Mar 19, 2016 · Syntocinon. The injection given to speed up the delivery of the placenta. This drug makes the womb contract and helps to prevent the heavy bleeding that some women may experience without it. Back to virtual tour of maternity services. Site policies. Report a problem with this page;
https://www.ncbi.nlm.nih.gov/pubmed/8930795/
Human placental transport of oxytocin. Malek A(1), Blann E, Mattison DR. Author information: (1)Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, USA. Oxytocin (OX) has been suggested as a signal for parturition.Author: Antoine Malek, Antoine Malek, Ernice Blann, Ernice Blann, Donald R. Mattison, Donald R. Mattison
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