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https://www.mdedge.com/obgyn/article/64781/obstetrics/routine-use-oxytocin-birth-just-right-amount-prevent-postpartum
The optimal interval for administering the oxytocin IV infusion has not been well studied. I recommend the infusion be continued for at least 4 hours following delivery. My recommendation is based on the observation that when oxytocin is discontinued shortly after birth, the risk of a delayed postpartum hemorrhage increases significantly.
https://www.drugs.com/pro/syntocinon.html
Jun 21, 2019 · Intravenous Infusion (Drip Method): To control postpartum bleeding, 10-40 units of oxytocin may be added to 1,000 mL of a non-hydrating diluent and run at a rate necessary to control uterine atony. Intramuscular Administration: 1 mL (10 units) of oxytocin can be given after delivery of the placenta. C. Treatment of Incomplete or Inevitable Abortion
https://bnf.nice.org.uk/drug/oxytocin.html
By intravenous infusion. For Adult. Initially 0.001–0.004 unit/minute, not to be started for at least 6 hours after administration of vaginal prostaglandin, dose increased at intervals of at least 30 minutes until a maximum of 3–4 contractions occur every 10 minutes (0.01 units/minute is often adequate) up to max. 0.02 units/minute, if regular contractions not established after a total 5 ...
https://www.drugs.com/dosage/syntocinon.html
Jul 08, 2019 · Intravenous Infusion (Drip Method): To control postpartum bleeding, 10-40 units of oxytocin may be added to 1,000 mL of a non-hydrating diluent and run at a rate necessary to control uterine atony. Intramuscular Administration: 1 mL (10 units) …
https://www.medicines.org.uk/emc/product/9735/smpc
Prevention of postpartum uterine haemorrhage: The usual dose is 5 IU by i.v. infusion (5 IU diluted in physiological electrolyte solution and administered as an i.v. drip infusion or, preferably, by means of a variable-speed infusion pump over 5 minutes) after delivery of the placenta.
https://www.mdedge.com/familymedicine/article/63401/prophylactic-oxytocin-or-after-placental-delivery
A much smaller double-blinded RCT found that PPH occurred significantly less often when oxytocin was delayed until after delivery of the placenta. 3 The study comprised 51 patients; 27 received 10 units of oxytocin on delivery of the anterior shoulder and 24 received an identical dose after delivery of the placenta. The incidence of PPH ≥500 mL was 0% when oxytocin was given after delivery ...
https://onlinelibrary.wiley.com/doi/full/10.1111/1552-6909.12528
Nov 24, 2014 · Administer IV oxytocin by providing a bolus dose followed by a total minimum infusion time of 4 hours after birth. For women who are at high risk for a postpartum hemorrhage or who have had cesarean births, continuation beyond 4 hours is recommended. ... placenta when oxytocin was given at the time of the delivery of the anterior shoulder ...
http://www.pphproject.org/downloads/awhonn_oxytocin.pdf
• Provide a minimum infusion time of 4 hours after delivery. • Give oxytocin 10 units intramuscularly (Im) in women without intravenous (IV) access. • for woman who are at high risk for a postpartum hemorrhage or who have had cesarean births, continuation beyond 4 hours is recommended.File Size: 88KB
https://reference.medscape.com/drug/pitocin-oxytocin-343132
Medscape - Indication-specific dosing for Pitocin (oxytocin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.
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