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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718568/
Mar 06, 2013 · Synergetic Targeted Delivery of Sleeping-Beauty Transposon System to Mesenchymal Stem Cells Using LPD Nanoparticles Modified with a Phage-Displayed Targeting Peptide Kun Ma, Dong-Dong Wang, Yiyang Lin, Jianglin Wang, Dr. Valery Petrenko, and Prof. Chuanbin MaoAuthor: Kun Ma, Dong Dong Wang, Yiyang Lin, Jianglin Wang, Valery Petrenko, Chuanbin Mao
https://www.onlinelibrary.wiley.com/doi/10.1002/adfm.201102963
An important criterion for effective gene therapy is sufficient chromosomal integration activity. The Sleeping Beauty (SB) transposon system is a plasmid system allowing efficient insertion of transgenes into the host genome. However, such efficient insertion occurs only after the system is delivered to nuclei.Author: Kun Ma, Dong Dong Wang, Yiyang Lin, Jianglin Wang, Valery Petrenko, Chuanbin Mao
https://www.ncbi.nlm.nih.gov/pubmed/23885226
Mar 06, 2013 · Synergetic Targeted Delivery of Sleeping-Beauty Transposon System to Mesenchymal Stem Cells Using LPD Nanoparticles Modified with a Phage-Displayed Targeting Peptide. Ma K(1), Wang DD, Lin Y, Wang J, Petrenko V, Mao C.Author: Kun Ma, Dong Dong Wang, Yiyang Lin, Jianglin Wang, Valery Petrenko, Chuanbin Mao
http://onlinelibrary.wiley.com/doi/10.1002/adfm.201102963/full
Synergetic Targeted Delivery of Sleeping‐Beauty Transposon System to Mesenchymal Stem Cells Using LPD Nanoparticles Modified with a Phage‐Displayed Targeting Peptide Kun Ma Department of Chemistry and Biochemistry, University of Oklahoma, Stephenson Life Sciences Research Center, 101 Stephenson Parkway, Norman, OK 73019, USA
https://www.researchgate.net/publication/251879127_Synergetic_Targeted_Delivery_of_Sleeping-Beauty_Transposon_System_to_Mesenchymal_Stem_Cells_Using_LPD_Nanoparticles_Modified_with_a_Phage-Displayed_Targeting_Peptide
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https://www.sciencedirect.com/science/article/pii/S0142961216307530
Sleeping Beauty (SB) transposon system is a kind of natural, nonviral gene delivery vehicles capable of achieving efficient genomic insertion , . It is a plasmid-based system constituting a transposon and a transposase that can insert a specific fragment of DNA into genomes of cells in a cut-and-paste fashion.Author: Kun Ma, Kun Ma, Duo Fu, Dongli Yu, Changhao Cui, Li Wang, Zhaoming Guo, Chuanbin Mao, Chuanbin Mao
https://www.ncbi.nlm.nih.gov/pubmed/28081459
1. Biomaterials. 2017 Mar;121:55-63. doi: 10.1016/j.biomaterials.2016.12.033. Epub 2017 Jan 2. Targeted delivery of in situ PCR-amplified Sleeping Beauty transposon genes to cancer cells with lipid-based nanoparticle-like protocells.Author: Kun Ma, Kun Ma, Duo Fu, Dongli Yu, Changhao Cui, Li Wang, Zhaoming Guo, Chuanbin Mao, Chuanbin Mao
https://www.researchgate.net/publication/312078673_Targeted_delivery_of_in_situ_PCR-amplified_Sleeping_Beauty_transposon_genes_to_cancer_cells_with_lipid-based_nanoparticle-like_protocells
Targeted delivery of in situ PCR-amplified Sleeping Beauty transposon genes to cancer cells with lipid-based nanoparticle-like protocells Article in Biomaterials 121 · January 2017 with 16 Reads
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623027/
Sleeping Beauty transposon system consists of a transposon that carries gene(s) of interest and a transposase that recognizes, excises, and reinserts genes in given location of the genome. It can create both gain-of-function and loss-of-function mutations, thus being frequently chosen to investigate the etiological mechanisms and gene therapy ...Author: Xiaomei Hou, Yan Du, Yang Deng, Jianfeng Wu, Guangwen Cao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095056/
Apr 15, 2011 · Over the past decade, the Sleeping Beauty (SB) transposon system has been developed as the leading non-viral vector for gene therapy. This vector combines the advantages of viruses and naked DNA. Here we review progress over the last 2 years in vector design, methods of delivery and safety that have supported its use in the clinic.Author: Elena L. Aronovich, R. Scott McIvor, Perry B. Hackett
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