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https://www.sciencedirect.com/topics/materials-science/micelle
The CMC is therefore defined as the concentration of surfactant at a given temperature where the first micelle begins to form [38]. Polymers also form micelles if the polymeric chain consists of hydrophilic and hydrophobic chains in the backbone. ... In 1984, H. Ringsdorf's group pioneered the use of polymeric micelles for drug delivery; in ...
https://www.sciencedirect.com/science/article/pii/S0168365901002991
The basic mechanisms underlying micelle longevity and steric protection in vivo are considered with a special emphasis on long circulating drug delivery systems. Advantages and disadvantages of micelles when compared with other drug delivery systems are considered.Author: Vladimir P. Torchilin
https://www.hindawi.com/journals/jdd/2013/340315/
Oral administration is the most commonly used and readily accepted form of drug delivery; however, it is find that many drugs are difficult to attain enough bioavailability when administered via this route. Polymeric micelles (PMs) can overcome some limitations of the oral delivery acting as carriers able to enhance drug absorption, by providing (1) protection of the loaded drug from the harsh ...Author: Wei Xu, Peixue Ling, Tianmin Zhang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155159/
Drug delivery to the intraocular tissues continues to be a challenging task. Nonetheless, recent advancements in the field of nanotechnology based novel delivery systems are being designed to fulfil these unmet needs. In the present review, we have discussed applicability of nanomicelles in controlled ocular drug delivery (ODD).
https://www.unmc.edu/pharmacy/faculty/pharmaceutical-sciences/docs/v5.pdf
used to prepare self-assembled polymer micelles for drug delivery,9,15,16 although the use of graft copolymers has been reported.17-19 For drug delivery purposes, the individual ure designed to be nimers a biodegradable20, 21 and/or have a low enough molecular mass (<~40 kDa) to be eliminated by renal clearance in order to avoid polymer
http://www.authorstream.com/Presentation/Omarmarwa-1404778-micelle-drug-delivery/
Micelle Drug Delivery - authorSTREAM Presentation. PowerPoint Presentation: Lyophilic colloids In this type of colloids sols, the dispersed phase has great attraction for the dispersion medium.
https://pubs.rsc.org/en/content/articlehtml/2014/ra/c3ra47370h
Polymeric micelles excel other drug carriers due to their small size and lower CMC values. 33–37 The average hydrodynamic diameter of spherical pluronics micelle is approximately 2 to 30 nm and aggregation number of 10 to 100. 38–42 Micelles of single type pluronics copolymer dominated all drug delivery efforts until recent years, but lately the binary systems drew the utmost attention.Author: Zaheer Ahmad, Afzal Shah, Afzal Shah, Muhammad Siddiq, Heinz-Bernhard Kraatz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874033/
May 19, 2016 · Surfactant-stripped induced frozen micelles (ss-InFroMs) Pluronic F127 (F127) has a concentration-sensitive critical micellar temperature (CMT) 33.The approach of modulating temperatures above and below Pluronic CMT was used to reversibly and thermochromically switch near infrared (NIR) dyes from nanoparticulate to microcrystalline form 34.We found that a hydrophobic NIR dye, …Author: Yumiao Zhang, Wentao Song, Jumin Geng, Upendra Chitgupi, Hande Unsal, Jasmin Federizon, Javid Rzayev...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071246/
Jul 20, 2018 · Micelles as colloidal suspension have attracted considerable attention due to their potential use for both cancer diagnosis and therapy. These structures have proven their ability to deliver poorly water-soluble anticancer drugs, improve drug stability, and have good penetration and site-specificity, leading to enhance therapeutic efficacy.
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