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https://pubs.acs.org/doi/10.1021/bc015575f
Overcoming the barriers to efficient gene transfer is a fundamental goal of biotechnology. A versatile approach to enhance the delivery of nonviral DNA involves complexation with cationic polymers, which can be designed to overcome the barriers to effective gene transfer. More recently, DNA release from a polymer substrate or scaffold has been shown to enhance gene transfer, likely by ...
https://www.researchgate.net/publication/11361394_Surface-Tethered_DNA_Complexes_for_Enhanced_Gene_Delivery
Request PDF Surface-Tethered DNA Complexes for Enhanced Gene Delivery Overcoming the barriers to efficient gene transfer is a fundamental goal of biotechnology. A versatile approach to enhance ...
https://scholars.duke.edu/display/pub1299834
Surface-tethered DNA complexes for enhanced gene delivery. ... Surface tethering of DNA represents a promising approach to enhancing gene transfer and spatially controlling gene delivery, which may have applications to a multitude of fields ranging from tissue engineering to functional genomics. Full Text.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732109/
In the present study, silk-based block copolymers were bioengineered with poly(l-lysine) domains for gene delivery. Ionic complexes of these silk-polylysine based block copolymers with plasmid DNA (pDNA) were prepared for gene delivery to human embryonic kidney (HEK) cells.Author: Keiji Numata, Balajikarthick Subramanian, Heather A. Currie, David L. Kaplan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621072/
Segura T, Shea LD. Surface-tethered DNA complexes for enhanced gene delivery. Bioconjugate Chem. 2002; 13:621–629. An early paper describing an approach to the adsorption of polyplexes to surfaces using specific and high-affinity biotin-streptavidin interactions, as opposed to non-specific electrostatic or hydrophobic interactions.Author: Christopher M. Jewell, David M. Lynn
https://www.sciencedirect.com/science/article/pii/S135902940800040X
T. Segura, L.D. SheaSurface-tethered DNA complexes for enhanced gene delivery Bioconjug Chem, 13 (2002), pp. 621-629 An early paper describing an approach to the adsorption of polyplexes to surfaces using specific and high-affinity biotin–streptavidin interactions, as opposed to non-specific electrostatic or hydrophobic interactions.Author: Christopher M. Jewell, David M. Lynn
https://www.sciencedirect.com/science/article/pii/S1742706107001237
Surface polyethylene glycol enhances substrate-mediated gene delivery by nonspecifically immobilized complexes. Author links open overlay panel Angela K. Pannier a Julie A. Wieland b Lonnie D. Shea b c. Show more. ... L.D. SheaSurface-tethered DNA complexes for enhanced gene delivery.Author: Angela K. Pannier, Julie A. Wieland, Lonnie D. Shea
https://link.springer.com/protocol/10.1007%2F978-1-4939-9092-4_12
Mar 06, 2019 · This chapter includes protocols for surface-mediated DNA delivery focusing on the simplest and most effective methods, which include nonspecific immobilization of DNA complexes (both polymer and lipid vectors) onto serum-coated cell culture polystyrene and self-assembled monolayers (SAMs) of alkanethiols on gold.Author: Angela K. Pannier, Tatiana Segura
https://segura.pratt.duke.edu/publications?s=year&o=asc
" Surface-tethered DNA complexes for enhanced gene delivery." Bioconjugate Chemistry 13, no. 3 (2002): 621-629. 2003. T Segura, MJ Volk, and LD Shea. " Substrate-mediated DNA delivery: role of the cationic polymer structure and extent of modification. ... " Gene delivery through cell culture substrate adsorbed DNA complexes.
https://www.researchgate.net/publication/232256464_Surface-_and_Hydrogel-Mediated_Delivery_of_Nucleic_Acid_Nanoparticles
Surface- and Hydrogel-Mediated Delivery of Nucleic Acid Nanoparticles. ... refers to the delivery of nucleic acid nanoparticles from a ... Surface-tethered DNA complexes for enhanced gene delivery ...
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