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https://link.springer.com/protocol/10.1385/1-59745-168-1:107
Encapsulating DNA within degradable delivery vehicles such as micro- or nanospheres provides an effective way to protect the DNA from the surrounding environment prior to delivery. The ability to... Surface-Modified Biodegradable Microspheres for DNA Vaccine Delivery SpringerLinkAuthor: Mark E. Keegan, W. Mark Saltzman
https://www.researchgate.net/publication/6806885_Surface-modified_biodegradable_microspheres_for_DNA_vaccine_delivery
Surface-modified biodegradable microspheres for DNA vaccine delivery Article · Literature Review (PDF Available) in Methods in molecular medicine 127:107-13 · February 2006 with 38 Reads
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195413/
Biodegradable polymer nanoparticles (NPs) are a promising approach for intracellular delivery of drugs, proteins, and nucleic acids, but little is known about their intracellular fate, particularly in epithelial cells, which represent a major target.Author: Malgorzata S. Cartiera, Katherine M. Johnson, Vanathy Rajendran, Michael J. Caplan, W. Mark Saltzman
https://www.sciencedirect.com/science/article/pii/S0264410X08002314
Surface modified liposomes for nasal delivery of DNA vaccine. ... vaccine delivery at these sites could provide a first line of defence against infectious diseases. The mucosal surfaces are rich in B-cells, T-cells and plasma cells and such antigen-reactive cells are essential for the induction and maintenance of specific immune responses ...Author: Kapil Khatri, Amit K. Goyal, Prem N. Gupta, Neeraj Mishra, Abhinav Mehta, Suresh P. Vyas
https://www.researchgate.net/publication/5457061_Surface_modified_liposomes_for_nasal_delivery_of_DNA_vaccine
To improve the DNA vaccine delivery efficiency of liposomes for intranasal administration, Khatri et al. modified the surface of liposomes by coating with glycol chitosan [173]. The major function ...
https://saltzmanlab.yale.edu/publications
Keegan ME and Saltzman WM. Surface modified biodegradable microspheres for DNA vaccine delivery, in DNA Vaccines, Saltzman, Brandsma, Shen (Ed), (2006). Also Methods in Molecular Medicine 127:107-113 (2006). PMID: 16988450
https://link.springer.com/book/10.1385/1597451681
DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514183/
Biodegradable polymeric microspheres are suitable for mucosal administration because the spheres can prevent antigens from low pH, bile salts, and digestive enzymes present in the gastrointestinal tracts. 40 PLGA and poly (lactide) (PLA) have been developed for vaccine delivery through the gastrointestinal tract and nasal cavity. 41,42 The ...Author: Chi-Ying Lin, Shih-Jie Lin, Yi-Chen Yang, Der-Yuan Wang, Hwei-Fang Cheng, Ming-Kung Yeh
https://www.sciencedirect.com/science/article/pii/S0264410X06000089
May 08, 2006 · Surface-modified dl-lactide/glycolide copolymer (PLGA) microspheres with chitosan (CS) were developed for nasal immunization using recombinant Hepatitis B (HBsAg) surface protein for the induction of humoral, cellular and mucosal immunity.Modified PLGA microspheres were characterized in vitro for their size, shape, entrapment efficiency and zeta potential.Author: K.S. Jaganathan, Suresh P. Vyas
http://catdir.loc.gov/catdir/toc/ecip066/2006000446.html
Table of contents for DNA vaccines : methods and protocols / edited by Mark W. Saltzman, Hong Shen, Janet L. Brandsma. ... DNA VACCINE DELIVERY SYSTEMS 6 Delivery of DNA Vaccines Using Electroporation Shawn Babiuk, Sylvia van Drunen Little-van den Hurk, and Lorne Babiuk 7 Needle-Free Injection of DNA Vaccines Kanakatte Raviprakash and Kevin ...
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