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http://ijpsr.com/bft-article/self-emulsifying-drug-delivery-system-a-review/?view=fulltext
Self-Micro Emulsifying Drug Delivery System (SMEDDS): SMEDDS are micro-emulsions formed by the SEDDS. It is thermodynamically stable and forms optically transparent emulsion. The major difference between micro-emulsions and common emulsions is mainly due to particle size of droplets.
https://www.sciencedirect.com/science/article/pii/S0378517317304489
Self-emulsifying drug delivery systems are complex lipid based drug delivery systems composed of a mixture of oils (lipids), surfactants, and optionally co-surfactants and co-solvents. These systems are typically self-dispersing, thus having the ability to form fine oil-in-water (O/W) emulsions or microemulsions (nanoemulsions)...Author: J. Mandić, A. Zvonar Pobirk, F. Vrečer, M. Gašperlin
https://www.dovepress.com/supersaturable-solid-self-microemulsifying-drug-delivery-system-precip-peer-reviewed-fulltext-article-IJN
Abstract: Solid self-emulsifying drug delivery system (SSEDDS), which incorporates liquid SEDDS into a solid dosage form, has been recently introduced to improve the oral bioavailability of poorly water-soluble drugs. However, supersaturated drug generated by SSEDDS is thermodynamically unstable and tends to precipitate rapidly prior to absorption, resulting in compromised bioavailability.Author: Guilan Quan, Boyi Niu, Vikramjeet Singh, Yixian Zhou, Chuan-Yu Wu, Xin Pan, Chuanbin Wu
https://www.hindawi.com/journals/jnm/2016/3642418/
Solid-self-emulsifying drug delivery system (S-SEDDS) of paclitaxel (Ptx) was developed by the spray drying method with the purpose of improving the low bioavailability (BA) of Ptx. 10% oil (ethyl oleate), 80% surfactant mixture (Tween 80 : Carbitol, 90 : 10, w/w), and 10% cosolvent (PEG 400) were chosen according to their solubilizing capacity.Author: Hea-Young Cho, Jun-Hyuk Kang, Lien Ngo, Phuong Tran, Yong-Bok Lee
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1191.pdf
emulsifiers and co‐emulsifiers in SEDDS and self‐micro emulsifying drug delivery systems (SMEDDS). They are gelatin well‐suited for filling into both soft and hard gelatin or into HPMC capsules. Thermo‐softening excipients, which melt in the range of 26‐70 0C
https://www.researchgate.net/publication/303173980_Self-emulsifying_drug_delivery_system_A_review
drug delivery, and solid self-emulsifying drug delivery system. POTENTIAL BENEFITS OF SEDDS OVER OTHER APPROACHES [1] Various other f ormulations like micronization, s olid …
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/self-microemulsifying-drug-delivery-system
Solid self-emulsifying drug delivery systems combine the advantages of liquid formulation (i.e., enhanced solubility and bioavailability) with those of solid dosage forms (e.g., low production cost, convenience of process control, high stability and reproducibility, and better patient compliance).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241625/
In vitro drug release of solid-self-microemulsifying drug delivery system after stability study CONCLUSION Self-microemulsifying drug delivery system is a vital tool in overcoming the formulation difficulties and improving the oral bioavailability of hydrophobic/lipophilic drugs.
https://pharmawiki.in/ppt-self-emulsifying-drug-delivery-systems-sedds/
Jan 13, 2014 · Contents of the powerpoint on Self Emulsifying Drug Delivery Systems (SEDDS) include: INTRODUCTION DEFINITION AND ADVANTAGES FORMULATION OF SEDDS PREPARATION OF SEDDS MECHANISM OF SELF EMULSIFICATION IN VITRO EVALUATION OF SEDDS IMPROVEMENT OF ORAL ABSORPTION BY SEDDS APPLICATIONS OF SEDDS SOLID …
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