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https://www.researchgate.net/publication/12125945_Site-Specific_Drug_Delivery_in_the_Gastrointestinal_Tract
Remote controlled capsule (RCC) has been extensively used in the field of site-specific drug delivery. It is a potent tool to study the regional drug absorption of the gastrointestinal (GI) tract...
https://pdfs.semanticscholar.org/344b/d81945821ee809e2825f4597208b192c9917.pdf
of site-specific gastrointestinal drug delivery. The first is the discovery that E. coli microbes specifically adhere to the follicle-associated epithelium (FAE) that overlies the ileal Peyer’s patches (Figure 1) in the gastrointestinal tract [14,15]. Peyer’s patches are GI immune nodules,
https://onlinelibrary.wiley.com/doi/10.1211/0022357056172
Both drug substances are intended to act locally at the inflamed sites of the gastrointestinal tract. The therapeutic objective for per oral treatment with these drugs is to achieve a high concentration of the active drug at the sites of inflammation while minimizing systemic absorption.Author: Sandra Klein, Jürgen Stein, Jennifer Dressman
http://europepmc.org/abstract/MED/11204736
Jan 01, 2000 · In recent years there has been a significant increase in available strategies for site-specific delivery in the gastrointestinal tract both to maximize a therapeutic response and to …Author: Ian R. Wilding
https://www.ncbi.nlm.nih.gov/pubmed/15969925
Both drug substances are intended to act locally at the inflamed sites of the gastrointestinal tract. The therapeutic objective for per oral treatment with these drugs is to achieve a high concentration of the active drug at the sites of inflammation while minimizing systemic absorption.Author: Sandra Klein, Jürgen Stein, Jennifer Dressman
https://www.sciencedirect.com/science/article/pii/016836599500057F
They contained both acidic comonomer and enzymatically degradable azoaromatic crosslinks. Such hydrogels are suitable for colon-specific drug delivery. In the low pH range of the stomach, the swelling of the gel is low and the drug is protected against digestion by enzymes.Author: Ping Yang Yeh, Malcolm M. Berenson, Wade S. Samowitz, Pavla Kopečková, Jindřich Kopecek
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